6-Bromo-2-nitro-3-pyridinol

Basic Information

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CAS Number

443956-08-9

Molecular Formula

C5H3BrN2O3

Molecular Weight

218.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

413℃ at 760 mmHg

SMILES

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C1=CC(=NC(=C1O)[N+](=O)[O-])Br

InChI

InChI=1S/C5H3BrN2O3/c6-4-2-1-3(9)5(7-4)8(10)11/h1-2,9H

InChIKey

GSGNTVQLHGOEMB-UHFFFAOYSA-N

LogP

1.98110

Complexity

160

Synonyms & References

English

FT-0688419
443956-08-9
GSGNTVQLHGOEMB-UHFFFAOYSA-N
6-Bromo-3-hydroxy-2-nitropyridine
SY042932
MFCD09261204
EN300-100316
AC-25459
SCHEMBL1809848
AKOS015920201
3-Pyridinol, 6-bromo-2-nitro-
BCP23445
2-BROMO-5-HYDROXY-6-NITROPYRIDINE
6-BROMO-2-NITRO-PYRIDIN-3-OL
SCHEMBL19122111
DTXSID00619212
A848135
CS-W006076
AB50069
6-Bromo-2-nitropyridin-3-ol
6-Bromo-3-hydroxy-2-nitropyridine;6-Bromo-2-nitropyridin-3-ol
J-518343
AMY8942
2-Bromo-5-hydroxy-6-nitropyridine
3-Pyridinol,6-bromo-2-nitro-
6-Bromo-2-nitro-pyridin-3-ol
KSC495Q7D
2-nitro-3-hydroxy-6-bromopyridine
STL557862
SBB055611
BBL104048

MDL Number

MFCD09261204

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9)?

6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9) is a crystalline solid with a molecular weight of approximately 217.03 g/mol. It is slightly soluble in water and has a pKa of about 6.5. Chemically, it is highly reactive, particularly towards nucleophilic substitution reactions at the bromine substituent and nitro group.

How is 6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9) typically synthesized?

6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9) is typically synthesized via the nitration of 6-bromo-3-pyridinol followed by reduction of the nitro group. Common methods include the use of concentrated nitric acid and sulfuric acid as the nitration reagent, and subsequent reduction with sodium borohydride or other mild reducing agents.

What industries use 6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9)?

6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9) finds applications in the pharmaceutical industry, particularly in the synthesis of certain drugs and intermediates. It is also used in the polymer industry for the development of new materials and in the sensor industry for the fabrication of gas-sensitive devices.

What precautions should be taken when handling 6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9)?

When handling 6-Bromo-2-nitro-3-pyridinol (CAS: 443956-08-9), it is crucial to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. Spills should be handled carefully, and the material safety data sheet (MSDS) should be referenced for detailed emergency procedures.