5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine | CAS No. 112897-99-1

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine

Basic Information

CAS Number

112897-99-1

Molecular Formula

C30H31N3O7

Molecular Weight

545.59 g/mol

AD

Basic Physical Properties

Boiling Point

742.535 °C at 760 mmHg

Flash Point

742.535 °C at 760 mmHg

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=NC5=O)N)O)O

InChI

InChI=1S/C30H31N3O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-26(34)27(35)28(40-24)33-17-16-25(31)32-29(33)36/h3-17,24,26-28,34-35H,18H2,1-2H3,(H2,31,32,36)/t24-,26-,27-,28-/m1/s1

InChIKey

SUENBDLQORXVMC-YULOIDQLSA-N

LogP

2.4706

Topological Polar Surface Area

138.29 Ų

Hydrogen Bond Donor/Acceptor

4 / 10

Complexity

883

Synonyms & References

English

  • 112897-99-1
  • Cytidine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (9CI)
  • FT-0771830
  • 4-Amino-1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidin-2-one
  • SCHEMBL5710025
  • F86539
  • 5'-O-[bis-(4-Methoxyphenyl)phenylmethyl]-cytidine
  • 4-Amino-1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
  • AKOS015908795
  • 5'-O-(4,4'-dimethoxytrityl)-cytidine
  • 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine
  • 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
  • Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-
  • 5’-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine
  • 5'-O-(4,4'-Dimethoxytrityl)cytidine
  • Cytidine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-

MDL Number

MFCD00057912

FAQ

What are the physical and chemical properties of 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine (CAS: 112897-99-1)?

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine is a white or off-white crystalline solid with a molecular weight of approximately 632.53 g/mol. It has a limited solubility in water and is soluble in common organic solvents like methanol and ethanol. This compound is relatively stable under normal conditions but can degrade in acidic or basic environments. It shows moderate reactivity towards nucleophilic substitution reactions.

How is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine (CAS: 112897-99-1) typically synthesized?

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine is typically synthesized through a series of reactions involving the coupling of 5'-cytidine with bis(4-methoxyphenyl)(phenyl)methyl chloride. The synthesis can be carried out under anhydrous conditions using a suitable catalyst, such as 4-(dimethylamino)pyridine (DMAP), to enhance the coupling reaction. The overall yield can vary but is generally around 70-80%.

What industries use 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine (CAS: 112897-99-1)?

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine is primarily used in the pharmaceutical industry for the development of novel therapeutic agents. It is also of interest in the polymer industry for its potential use as a monomer. Additionally, it may have applications in sensors and semiconductors due to its chemical stability and reactivity.

What precautions should be taken when handling 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine (CAS: 112897-99-1)?

When handling 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine, protective gloves, goggles, and a lab coat should be worn. It should be stored in a dry environment and handled in a well-ventilated area or a fume hood. In case of spills, they should be cleaned up immediately, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.

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