2-Bromo-3-isopropoxypyridine

Basic Information

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CAS Number

113503-65-4

Molecular Formula

C8H10BrNO

Molecular Weight

216.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC(C)OC1=C(N=CC=C1)Br

InChI

InChI=1S/C8H10BrNO/c1-6(2)11-7-4-3-5-10-8(7)9/h3-6H,1-2H3

InChIKey

OEYWNNYESKWLGO-UHFFFAOYSA-N

LogP

2.6313000000000004

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

119

Synonyms & References

English

2-Bromo-3-isopropoxypyridine
2-bromo-3-propan-2-yloxypyridine
AKOS014435133
E83144
SCHEMBL2861434
MFCD11878542
2-bromo-3-isopropyloxy pyridine
CS-0365312
Pyridine, 2-bromo-3-(1-methylethoxy)-
DTXSID70440757
DB-093657
113503-65-4
OEYWNNYESKWLGO-UHFFFAOYSA-N
2-Bromo-3-(1-methylethoxy)pyridine

MDL Number

MFCD11878542

FAQ

What are the physical and chemical properties of 2-Bromo-3-isopropoxypyridine (CAS: 113503-65-4)?

2-Bromo-3-isopropoxypyridine is a white crystalline solid with a molecular weight of 260.24 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. The compound is moderately reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored away from strong oxidizers and reducing agents.

How is 2-Bromo-3-isopropoxypyridine (CAS: 113503-65-4) typically synthesized?

2-Bromo-3-isopropoxypyridine is typically synthesized by the bromination of 3-isopropoxypyridine using N-bromosuccinimide (NBS) in an organic solvent like toluene. The reaction is carried out at room temperature with good yield and selectivity. Alternatively, it can be prepared by reacting 3-isopropoxypyridine with bromine in the presence of a cupric ion catalyst.

What industries use 2-Bromo-3-isopropoxypyridine (CAS: 113503-65-4)?

2-Bromo-3-isopropoxypyridine is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the preparation of materials for sensors and semiconductors due to its unique electronic properties. Additionally, it may have applications in the polymer industry for the development of new materials with specific properties.

What precautions should be taken when handling 2-Bromo-3-isopropoxypyridine (CAS: 113503-65-4)?

When handling 2-Bromo-3-isopropoxypyridine, safety glasses and gloves should be worn. It should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be carefully cleaned up and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and storage instructions.