Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate | CAS No. 1263059-26-2
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
Basic Information
CAS Number
1263059-26-2
Molecular Formula
C8H6ClN3O2
Molecular Weight
211.61 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
- AT27430
- 5,7-Dioxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
MDL Number
MFCD22209691
FAQ
What are the physical and chemical properties of Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS: 1263059-26-2)?
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate is a white crystalline solid with a molecular weight of approximately 285.03 g/mol. It is slightly soluble in water but highly soluble in organic solvents like ethanol and acetonitrile. This compound is known for its moderate reactivity, particularly towards nucleophilic substitution reactions. It exhibits a high melting point, suggesting a crystalline form that is stable under normal laboratory conditions.
How is Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS: 1263059-26-2) typically synthesized?
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate is synthesized through a multi-step process involving the condensation of 1-chloropyrazole with methyl pyrimidine-2-carboxylate. The reaction typically proceeds with a Lewis acid catalyst such as aluminum chloride to promote the electrophilic aromatic substitution. The yield of the product is usually around 75-85%, and the method is known for its high selectivity and good reproducibility.
What industries use Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS: 1263059-26-2)?
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate is used in the pharmaceutical industry for the synthesis of complex molecules and as an intermediate in drug development. It also has potential applications in the polymer industry for its potential use in developing new materials with specific properties. Additionally, it can be utilized in the sensor and semiconductor industries due to its electronic properties.
What precautions should be taken when handling Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS: 1263059-26-2)?
When handling Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize exposure to the air. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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