(2-Bromophenyl)methanesulfonyl chloride

Basic Information

View in Editor

CAS Number

24974-74-1

Molecular Formula

C7H6BrClO2S

Molecular Weight

269.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

78 °C

SMILES

View in Editor

C1=CC=C(C(=C1)CS(=O)(=O)Cl)Br

InChI

InChI=1S/C7H6BrClO2S/c8-7-4-2-1-3-6(7)5-12(9,10)11/h1-4H,5H2

InChIKey

RDRCWHIGMBAULL-UHFFFAOYSA-N

LogP

2.5177000000000005

Topological Polar Surface Area

34.14 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

234

Safety Information

View Safety Information

Hazard Statement

Synonyms & References

English

E76548
2-bromobenzylsulfonyl chloride, AldrichCPR
(2-bromophenyl)methanesulfonyl Chloride
(2-bromophenyl)methanesulphonyl chloride
CS-0156635
AKOS010079448
RDRCWHIGMBAULL-UHFFFAOYSA-N
Benzenemethanesulfonyl chloride, 2-bromo-
2-Bromobenzylsulfonylchloride
SCHEMBL271620
FS-5364
2-Bromobenzylsulfonyl chloride
2-bromobenzylsulphonyl chloride
MFCD06798044
FT-0660316
EN300-96185
24974-74-1
GEO-03862
(2-bromophenyl)methanesulfonylChloride
DTXSID30375778
(2-Bromophenyl)methanesulfonyl chloride
2-bromobenzylsulfonyl chloride
Benzenemethanesulfonylchloride, 2-bromo-
2-Brombenzylsulfonylchlorid

MDL Number

MFCD06798044

Customs Code

2904909090

FAQ

What are the physical and chemical properties of (2-Bromophenyl)methanesulfonyl chloride (CAS: 24974-74-1)?

(2-Bromophenyl)methanesulfonyl chloride is a solid at room temperature with a melting point of approximately 94-97°C. Its molecular weight is about 287.04 g/mol. The compound is poorly soluble in water but soluble in organic solvents like dichloromethane and ethanol. It is highly reactive, particularly towards nucleophiles, and can undergo sulfonation and bromination reactions.

How is (2-Bromophenyl)methanesulfonyl chloride (CAS: 24974-74-1) typically synthesized?

(2-Bromophenyl)methanesulfonyl chloride is usually synthesized by reacting 2-bromophenylmethane with methanesulfonyl chloride in the presence of a base like triethylamine. The reaction is typically carried out in dichloromethane under anhydrous conditions. The yield is high, and the product is isolated by acid work-up and recrystallization.

What industries use (2-Bromophenyl)methanesulfonyl chloride (CAS: 24974-74-1)?

(2-Bromophenyl)methanesulfonyl chloride is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer chemistry for the modification of polymers, and in sensor technology for the development of chemical sensors. Its reactivity makes it useful in various chemical transformations and derivatizations.

What precautions should be taken when handling (2-Bromophenyl)methanesulfonyl chloride (CAS: 24974-74-1)?

When handling (2-Bromophenyl)methanesulfonyl chloride, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat is necessary. The compound should be handled in a well-ventilated area or a fume hood due to its strong odor and potential reactivity. Spills should be cleaned up immediately with appropriate absorbents, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.