3-Quinolinylboronic acid

Basic Information

View in Editor

CAS Number

191162-39-7

Molecular Formula

C9H8BNO2

Molecular Weight

172.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

191-196 °C

Boiling Point

400.3°C at 760 mmHg

Flash Point

195.9℃

SMILES

View in Editor

B(C1=CC2=CC=CC=C2N=C1)(O)O

InChI

InChI=1S/C9H8BNO2/c12-10(13)8-5-7-3-1-2-4-9(7)11-6-8/h1-6,12-13H

InChIKey

YGDICLRMNDWZAK-UHFFFAOYSA-N

LogP

-0.08540000000000036

Topological Polar Surface Area

53.35 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

177

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class KEEP COLD Class KEEP COLD

Synonyms & References

English

Boronic acid, 3-quinolinyl-
AKOS003237476
A4218
J-521587
3-Quinolinyl-boronic acid
YGDICLRMNDWZAK-UHFFFAOYSA-N
DTXSID60370433
GS-6504
PB21802
SCHEMBL20226
(quinolin-3-yl)boronic acid
BCP21925
J-513104
Quinoline-3-boronic Acid
MFCD02183527
Z330820004
quinolin-3-yl-boronic acid
CHEMBL3236629
3-quinolylboronic acid
AM20050916
EN300-31679
3-Quinolineboronic acid, technical grade
SB20064
Quinolin-3-ylboronic Acid
CS-W002923
J-012350
F0001-2468
Quinoline-3-boronicacid
SY004117
Boronic acid, B-3-quinolinyl-
Q0080

MDL Number

MFCD02183527

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 3-Quinolinylboronic acid (CAS: 191162-39-7)?

3-Quinolinylboronic acid is a white crystalline solid with a molecular weight of approximately 267.3 g/mol. It is moderately soluble in water and ethanol. The compound exhibits good reactivity in boronate ester formation and undergoes electrophilic aromatic substitution reactions. It is commonly used in organic synthesis and as a chelating agent.

How is 3-Quinolinylboronic acid (CAS: 191162-39-7) typically synthesized?

3-Quinolinylboronic acid is typically synthesized via the reaction of 3-quinolineboronic acid and bromine in the presence of a base such as potassium hydroxide. The reaction conditions are optimized for high yield and selectivity, often employing microwave-assisted techniques to enhance reaction rates and conversion.

What industries use 3-Quinolinylboronic acid (CAS: 191162-39-7)?

3-Quinolinylboronic acid is used in the pharmaceutical industry for the synthesis of complex molecules and compounds with bioactive properties. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for its use in electronic device manufacturing. Additionally, it finds applications in the development of sensors and as a chelating agent in analytical chemistry.

What precautions should be taken when handling 3-Quinolinylboronic acid (CAS: 191162-39-7)?

When handling 3-Quinolinylboronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.