3-Quinolinylboronic acid(CAS: 191162-39-7)

3-Quinolinylboronic acid is a white crystalline solid with a molecular weight of approximately 267.3 g/mol. It is moderately soluble in water and ethanol. The compound exhibits good reactivity in boronate ester formation and undergoes electrophilic aromatic substitution reactions. It is commonly used in organic synthesis and as a chelating agent.

3-Quinolinylboronic acid is typically synthesized via the reaction of 3-quinolineboronic acid and bromine in the presence of a base such as potassium hydroxide. The reaction conditions are optimized for high yield and selectivity, often employing microwave-assisted techniques to enhance reaction rates and conversion.

3-Quinolinylboronic acid is used in the pharmaceutical industry for the synthesis of complex molecules and compounds with bioactive properties. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for its use in electronic device manufacturing. Additionally, it finds applications in the development of sensors and as a chelating agent in analytical chemistry.

When handling 3-Quinolinylboronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.