2,6-Dichloro-3-nitroaniline

Basic Information

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CAS Number

13785-48-3

Molecular Formula

C6H4Cl2N2O2

Molecular Weight

207.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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c1cc(c(c(c1N(=O)=O)Cl)N)Cl

InChI

InChI=1S/C6H4Cl2N2O2/c7-3-1-2-4(10(11)12)5(8)6(3)9/h1-2H,9H2

InChIKey

FYMVQJCDXFAPGG-UHFFFAOYSA-N

LogP

2.4838000000000005

Topological Polar Surface Area

69.16 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Synonyms & References

English

2,6-Dichloro-3-nitroaniline
2,6-Dichlor-3-nitroanilin
2,6-dichloro-3-nitro-aniline

MDL Number

MFCD11110683

Customs Code

2921420090

FAQ

What are the physical and chemical properties of 2,6-Dichloro-3-nitroaniline (CAS: 13785-48-3)?

2,6-Dichloro-3-nitroaniline is a crystalline solid with a molecular weight of approximately 222.02 g/mol. It is sparingly soluble in water and highly soluble in organic solvents like ethanol. This compound is unstable under basic conditions and can undergo hydrolysis. Common reactions include nitration and chlorination.

How is 2,6-Dichloro-3-nitroaniline (CAS: 13785-48-3) typically synthesized?

2,6-Dichloro-3-nitroaniline is synthesized through the nitration of 2,6-dichloroaniline using nitric acid and sulfuric acid as the nitrating agent. The reaction is conducted under controlled conditions to achieve high yield and selectivity. Catalysts like concentrated sulfuric acid are used to enhance the reaction rate and yield.

What industries use 2,6-Dichloro-3-nitroaniline (CAS: 13785-48-3)?

2,6-Dichloro-3-nitroaniline is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds application in the production of dyes, pigments, and as a precursor for the synthesis of other chemical intermediates. Additionally, it can be used in analytical chemistry as a reagent.

What precautions should be taken when handling 2,6-Dichloro-3-nitroaniline (CAS: 13785-48-3)?

When handling 2,6-Dichloro-3-nitroaniline, it is crucial to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. This compound should be used in a well-ventilated area or a fume hood due to its potential for fume generation. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.