2,6-Dichloro-3-nitroaniline(CAS: 13785-48-3)

2,6-Dichloro-3-nitroaniline is a crystalline solid with a molecular weight of approximately 222.02 g/mol. It is sparingly soluble in water and highly soluble in organic solvents like ethanol. This compound is unstable under basic conditions and can undergo hydrolysis. Common reactions include nitration and chlorination.

2,6-Dichloro-3-nitroaniline is synthesized through the nitration of 2,6-dichloroaniline using nitric acid and sulfuric acid as the nitrating agent. The reaction is conducted under controlled conditions to achieve high yield and selectivity. Catalysts like concentrated sulfuric acid are used to enhance the reaction rate and yield.

2,6-Dichloro-3-nitroaniline is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds application in the production of dyes, pigments, and as a precursor for the synthesis of other chemical intermediates. Additionally, it can be used in analytical chemistry as a reagent.

When handling 2,6-Dichloro-3-nitroaniline, it is crucial to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. This compound should be used in a well-ventilated area or a fume hood due to its potential for fume generation. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.