Csp3–F bond activation by nucleophilic attack of the {Pt2S2} core assisted by non-covalent interactions

Literature Information

Publication Date 2008-04-29
DOI 10.1039/B801889H
Impact Factor 6.222
Authors

Ainara Nova, Gregori Ujaque, Pilar González-Duarte, Agustí Lledós


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Abstract

The high nucleophilicity of the sulfur atoms in [Pt2(dppp)2(μ-S)2] triggers a C–F activation process in 1,3-difluoro-2-propanol that leads to the [Pt2(dppp)2(μ-S)(μ-SCH2CH(OH)CH2F]F product through a SN2 mechanism, where the O–H⋯F hydrogen bond established from the alcohol group of the organic substrate is essential for assisting the departure of the fluoride anion.

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