Latrepirdine Dihydrochloride

Basic Information

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CAS Number

97657-92-6

Molecular Formula

C21H27Cl2N3

Molecular Weight

392.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Solubility

H2O: ≥10mg/mL

SMILES

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CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl

InChI

InChI=1S/C21H25N3.2ClH/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;;/h4-7,12-13H,8-11,14H2,1-3H3;2*1H

InChIKey

GTWLIQOLGOZTLF-UHFFFAOYSA-N

LogP

4.727340000000006

Topological Polar Surface Area

21.060000000000002 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

425

Synonyms & References

English

Latrepirdine
1H-pyrido
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole,dihydrochloride
Dimebolin (hydrochloride)
Dimebolin dihydrochloride
Dimebon dihydrochloride
DIMEBONE HCL
Latrepirdine Dihydrochloride
Dimebolin
Dimebon,Latrepirdine
Dimebone dihydrochloride
Latrepirdine dihydrochloride (USAN)
Latrepirdine,Dimebolin,Dimebon
1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-, dihydrochloride (9CI)
1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-, dihydrochloride (7CI)
Dimeboline dihydrochloride
Latrepirdine dihydrochloride
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-3,6-dimethyl-9-(2-(6-methyl-3-pyridyl)ethyl)-, dihydrochloride
DTXSID10243103
Latrepirdine 2HCl
GLXC-01909
GTWLIQOLGOZTLF-UHFFFAOYSA-N
LATREPIRDINE DIHYDROCHLORIDE
2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride
Dimebone dihydrochloride hydrate
Q27270139
HY-14537
1H-PYRIDO(4,3-B)INDOLE, 2,3,4,5-TETRAHYDRO-2,8-DIMETHYL-5-(2-(6-METHYL-3- PYRIDINYL)ETHYL)-, HYDROCHLORIDE (1:2)
Dimebolin hydrochloride
DIMEBOLIN DIHYDROCHLORIDE [MI]

MDL Number

MFCD17215933

FAQ

What are the physical and chemical properties of Latrepirdine Dihydrochloride (CAS: 97657-92-6)?

Latrepirdine dihydrochloride is a crystalline compound with a molecular weight of approximately 454.7 g/mol. It is soluble in water and ethanol. This compound has moderate reactivity, especially in basic conditions, and should be handled with care to avoid unwanted reactions. Its stability in various solvents and pH conditions makes it suitable for pharmaceutical applications.

How is Latrepirdine Dihydrochloride (CAS: 97657-92-6) typically synthesized?

Latrepirdine dihydrochloride is typically synthesized through a multi-step process involving alkylation, cyclization, and hydrochloridation reactions. Common catalysts include sulfuric acid and palladium complexes. The reaction is selective and yields high purity products, making it suitable for pharmaceutical production.

What industries use Latrepirdine Dihydrochloride (CAS: 97657-92-6)?

Latrepirdine dihydrochloride is primarily used in the pharmaceutical industry for the development of therapeutic agents. It is also explored for its potential use in sensors and as a component in some semiconductor materials. Its applications in polymers are limited but show promise in certain specialized areas.

What precautions should be taken when handling Latrepirdine Dihydrochloride (CAS: 97657-92-6)?

When handling Latrepirdine dihydrochloride, use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Store it in a cool, dry place away from direct sunlight. In case of a spill, use appropriate fume hoods and follow safety data sheet (SDS) guidelines for disposal. Always ensure proper ventilation and follow all safety protocols to avoid inhalation or skin contact.