2-Methyl-1,2-thiazol-3(2H)-one - 5-chloro-2-methyl-1,2-thiazol-3(2H)-one (1:1) | CAS No. 96118-96-6
2-Methyl-1,2-thiazol-3(2H)-one - 5-chloro-2-methyl-1,2-thiazol-3(2H)-one (1:1)
Basic Information
CAS Number
96118-96-6
Molecular Formula
C8H9ClN2O2S2
Molecular Weight
264.76 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- ISOTHIAZOLINONE (MIT, CMIT)
- 5-chloro-2-methyl-1,2-thiazol-3-one
- 5-Chloro-2-methyl-4-isothiazolin-3-one-2-methyl-4-isothiazolin-3-one mixt.
- Isothiazolinone
- MIT
- CMIT
- 5-Chloro-2-methyl-4-isothiazolin-3-one
- 2-methyl-4-isothiazolin-3-one
- CIT
- MIT-1.5
- MIT-2.5
- MIT-3
- MIT-7
FAQ
What are the physical and chemical properties of 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6)?
5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6) is a white crystalline solid with a molecular weight of approximately 165.01 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is known for its high reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but should be stored away from moisture and heat to prevent degradation.
How is 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6) typically synthesized?
5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6) is typically synthesized via a condensation reaction between chloroacetyl chloride and 2-methylthiazole. The reaction is catalyzed by anhydrous aluminum chloride. The yield is around 85%, and the product is isolated by recrystallization from ethanol. The reaction is conducted under anhydrous conditions to ensure high purity and selectivity.
What industries use 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6)?
5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6) is used in various industries, including pharmaceuticals, where it serves as an intermediate in the synthesis of bioactive compounds. It is also used in the preparation of certain dyes and pigments, as well as in the synthesis of sensors and semiconductors due to its unique electronic properties.
What precautions should be taken when handling 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6)?
When handling 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or fume hood to avoid inhalation of vapors. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on safe handling and disposal.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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