Compound Q&A
How is 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6) typically synthesized?
Answer
5-Chloro-2-methyl-1,2-thiazol-3(2H)-one (CAS: 96118-96-6) is typically synthesized via a condensation reaction between chloroacetyl chloride and 2-methylthiazole. The reaction is catalyzed by anhydrous aluminum chloride. The yield is around 85%, and the product is isolated by recrystallization from ethanol. The reaction is conducted under anhydrous conditions to ensure high purity and selectivity.
About
CAS No
96118-96-6
English Name
2-Methyl-1,2-thiazol-3(2H)-one - 5-chloro-2-methyl-1,2-thiazol-3(2H)-one (1:1)
Molecular Formula
C8H9ClN2O2S2
Molecular Weight
264.76 g/mol
SMILES
Cn1c(=O)ccs1.Cn1c(=O)cc(s1)Cl
InChIKey
QYYMDNHUJFIDDQ-UHFFFAOYSA-N
Last Updated: 2026-03-10 19:33