(4-Chloro-3-methoxyphenyl)boronic acid

Basic Information

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CAS Number

89694-47-3

Molecular Formula

C7H8BClO3

Molecular Weight

186.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

No data available

Melting Point

151°C

Boiling Point

341.7±52.0 °C at 760 mmHg

Density

1.325

Flash Point

160.4±30.7 °C

Refractive Index

1.545

SMILES

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B(C1=CC(=C(C=C1)Cl)OC)(O)O

InChI

InChI=1S/C7H8BClO3/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,10-11H,1H3

InChIKey

DZNNRXURZJLARZ-UHFFFAOYSA-N

LogP

0.028399999999999648

Topological Polar Surface Area

49.69 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

145

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

(4-Chloro-3-methoxyphenyl)boronic acid
4-Chloro-3-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
4-chloro-3-methoxyphenylboronic acid
[4-chloro-3-(methyloxy)phenyl]boronic acid
4-Chlor-3-methoxy-benzol-boronsaeure
4-chloro-3-methoxybenzeneboronic acid
4-Chloro-3-methoxybenzeneboronic Acid (contains varying amounts of Anhydride)
(4-Chloro-3-Methoxyphenyl)Boronicacid
B-(4-Chloro-3-methoxyphenyl)boronic acid (ACI)
Benzeneboronic acid, 4-chloro-3-methoxy- (7CI)
Boronic acid, (4-chloro-3-methoxyphenyl)- (9CI)
4-Chloro-3-methoxyphenylboronic acid
(4-chloro-3-methoxyphenyl)boronic acid
SCHEMBL1018126
J-501383
NCGC00336368-01
Boronic acid, (4-chloro-3-methoxyphenyl)-
4-chloro-3-methoxyphenyl boronic acid
EN300-38917
MFCD01318965
C3253
4-Choro-3-methoxyphenylboronic acid
SY030547
4-chloro-3-methoxy phenylboronic acid
DZNNRXURZJLARZ-UHFFFAOYSA-N
AB01331104-02
4-chloro-3-methoxyphenylboronic acid, AldrichCPR
4-chloro-5-methoxyphenylboronic acid
4N-900
CS-W002768
Z360059556

MDL Number

MFCD01318965

Customs Code

2931900090

FAQ

What are the physical and chemical properties of (4-Chloro-3-methoxyphenyl)boronic acid (CAS: 89694-47-3)?

(4-Chloro-3-methoxyphenyl)boronic acid is a white crystalline solid with a molecular weight of approximately 228.04 g/mol. It is slightly soluble in water and ethanol. This compound displays good reactivity in boronate ester formation and is used as a boronic acid building block in organic synthesis. Its solubility and reactivity make it a valuable reagent in various chemical processes.

How is (4-Chloro-3-methoxyphenyl)boronic acid (CAS: 89694-47-3) typically synthesized?

(4-Chloro-3-methoxyphenyl)boronic acid is commonly synthesized through the coupling of 4-chloro-3-methoxybenzene with boron tribromide in a solvent like toluene. The reaction is generally carried out in the presence of a base such as sodium hydroxide to promote boronation. The yield and selectivity of the synthesis can be enhanced by optimizing reaction conditions and using appropriate catalysts.

What industries use (4-Chloro-3-methoxyphenyl)boronic acid (CAS: 89694-47-3)?

(4-Chloro-3-methoxyphenyl)boronic acid is primarily used in the pharmaceutical industry for the synthesis of new drugs and intermediates. It is also utilized in the polymer industry for the development of advanced materials. Additionally, this compound can be applied in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling (4-Chloro-3-methoxyphenyl)boronic acid (CAS: 89694-47-3)?

Handling (4-Chloro-3-methoxyphenyl)boronic acid should be done with appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure that all operations are conducted in a fume hood to minimize exposure to fumes. Spills should be carefully cleaned up using absorbent materials and appropriate waste handling procedures as per the safety data sheet (SDS). Always refer to the latest SDS for specific safety guidelines and emergency procedures.