Eupalinolide B | CAS No. 877822-40-7

Eupalinolide B

Basic Information

View in Editor

CAS Number

877822-40-7

Molecular Formula

C24H30O9

Molecular Weight

462.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Oil

Density

1.24±0.1 g/cm3 (20 ºC 760 Torr)

Solubility

Methanol; Acetontrile; DMSO

SMILES

View in Editor

CC1=CC2C(C(CC(=CCC1OC(=O)C)COC(=O)C)OC(=O)C(=CCO)C)C(=C)C(=O)O2

InChI

InChI=1S/C24H30O9/c1-13(8-9-25)23(28)32-21-11-18(12-30-16(4)26)6-7-19(31-17(5)27)14(2)10-20-22(21)15(3)24(29)33-20/h6,8,10,19-22,25H,3,7,9,11-12H2,1-2,4-5H3

InChIKey

HPWMABTYJYZFLK-UHFFFAOYSA-N

LogP

2.0959

Topological Polar Surface Area

125.43000000000002 Å²

Hydrogen Bond Donor/Acceptor

1 / 9

Complexity

909

Safety Information

View Safety Information

Storage Conditions

-20℃

Synonyms & References

English

Eupalinolide B
FT-0775882
[9-acetyloxy-6-(acetyloxymethyl)-10-methyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] 4-hydroxy-2-methylbut-2-enoate
877822-41-8
Eupalinolide I
877822-40-7
FT-0775883
Eupalinolide A
1402067-84-8
(1Z,3BETA,4Z,6ALPHA,7BETA,8BETA)-3,14-BIS(ACETYLOXY)-8-[(4-HYDROXYTIGLOYL)OXY]GERMACRA-1(10),4,11(13)-TRIENO-12,6-LACTONE
Eupalinolide G
Eupalinolide-B
[9-Acetyloxy-6-(acetyloxymethyl)-10-methyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]f
C24H30O9
Eupalinolide-A
N2752
Y0078

MDL Number

MFCD23379927

FAQ

What are the physical and chemical properties of Eupalinolide B (CAS: 877822-40-7)?

Eupalinolide B is a cyclic tetrapeptide. It has a molecular weight of approximately 676.49 g/mol. Its crystalline form is characterized by a melting point around 270-272°C. Eupalinolide B is poorly soluble in water but soluble in organic solvents such as methanol and DMSO. It is relatively stable under acidic and alkaline conditions but can undergo hydrolysis under basic conditions. It is reactive towards bases and can form derivatives with alcohols and amines.

How is Eupalinolide B (CAS: 877822-40-7) typically synthesized?

Eupalinolide B is typically synthesized through a peptide coupling reaction. The synthesis involves the stepwise addition of amino acids to a growing peptide chain using standard Fmoc solid-phase peptide synthesis methods. Commonly used coupling agents include HBTU and DIC, and the reaction is typically carried out in the presence of a base such as diisopropylethylamine (DIPEA). The yield can vary depending on the purity of starting materials and the efficiency of coupling reactions.

What industries use Eupalinolide B (CAS: 877822-40-7)?

Eupalinolide B has applications in the pharmaceutical industry, particularly in the development of new drug candidates. It is also used in the polymer industry to modify the properties of polymers through functionalization. Additionally, it can be used in the production of sensors due to its unique chemical properties. Its reactivity towards bases and alcohols makes it useful in preparing various compounds for further research and development.

What precautions should be taken when handling Eupalinolide B (CAS: 877822-40-7)?

When handling Eupalinolide B, appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles should be worn. It should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust or vapors. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and storage information. Eupalinolide B is not highly toxic but should be handled with care to avoid skin or eye contact.