Atorvastatin Epoxy Tetrahydrofuran Impurity | CAS No. 873950-19-7
Atorvastatin Epoxy Tetrahydrofuran Impurity
Basic Information
CAS Number
873950-19-7
Molecular Formula
C26H24FNO5
Molecular Weight
449.48 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Atorvastatin Epoxy Tetrahydrofuran Impurity
- (2Z)-2-(2-AMINOTHIAZOL-4-YL)-N-(FORMYLMETHYL)-2-(METHOXYIMINO)ACETAMIDE
- 4-(4-fluorophenyl)-2,4-dihydroxy-N,5-diphenyl-2-propan-2-yl-3,6-dioxabicyclo[3.1.0]hexane-1-carboxamide
- atorvastatin calcium epoxide dihydroxy
- ATV-epoxy furan
- 4-(4-Fluorophenyl)-2,4-dihydroxy-2-(1-methylethyl)-N,5-diphenyl-3,6-dioxabicyclo[3.1.0]hexane-1-carboxamide (ACI)
MDL Number
MFCD31700699
FAQ
What are the physical and chemical properties of Atorvastatin Epoxy Tetrahydrofuran Impurity (CAS: 873950-19-7)?
Atorvastatin Epoxy Tetrahydrofuran Impurity is a white to off-white crystalline solid with a molecular weight of approximately 404.44 g/mol. It has a low solubility in water but is soluble in many organic solvents. The impurity shows limited reactivity in typical organic reactions, and its stability is generally good under normal storage conditions. It is not flammable but should be handled with care in the presence of strong oxidizers or reducing agents.
How is Atorvastatin Epoxy Tetrahydrofuran Impurity (CAS: 873950-19-7) typically synthesized?
Atorvastatin Epoxy Tetrahydrofuran Impurity is typically synthesized through a series of stereoselective reactions, including epoxidation and cyclization steps. Common catalysts used in the synthesis include metal complexes and organocatalysts. The overall yield is around 50-60%, and the process involves careful monitoring of reaction conditions to ensure high selectivity and purity.
What industries use Atorvastatin Epoxy Tetrahydrofuran Impurity (CAS: 873950-19-7)?
Atorvastatin Epoxy Tetrahydrofuran Impurity is used primarily in the pharmaceutical industry as an impurity in the production of atorvastatin, a cholesterol-lowering drug. It may also find limited use in research and development for studies on lipid metabolism and related pathways.
What precautions should be taken when handling Atorvastatin Epoxy Tetrahydrofuran Impurity (CAS: 873950-19-7)?
When handling Atorvastatin Epoxy Tetrahydrofuran Impurity, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly cleaned. Always refer to the safety data sheet (SDS) for detailed information on handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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