(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid | CAS No. 865352-21-2
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid
Basic Information
CAS Number
865352-21-2
Molecular Formula
C21H21NO4
Molecular Weight
351.4 g/mol
AD
Basic Physical Properties
Density
1.222
Synonyms & References
English
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-enoic acid
- (R)-N-FMOC-2-(3'-BUTENYL)GLYCINE
- (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid
MDL Number
MFCD17215631
FAQ
What are the physical and chemical properties of (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid (CAS: 865352-21-2)?
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid is a white to off-white crystalline solid with a molecular weight of approximately 398.39 g/mol. It has a moderate solubility in common organic solvents like methanol and ethanol, but is poorly soluble in water. The compound is chemically reactive, particularly towards nucleophiles, and exhibits ester and amide functional groups typical of its structure.
How is (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid (CAS: 865352-21-2) typically synthesized?
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid is typically synthesized through multistep reactions starting from fluorenylmethanol and hex-5-enoic acid, involving protection, acylation, and deprotection steps. Commonly used catalysts include strong bases like diisopropylethylamine, and the overall yield is usually around 70-80%. Selectivity for the desired stereoisomer is achieved through careful control of reaction conditions.
What industries use (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid (CAS: 865352-21-2)?
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid is primarily used in the pharmaceutical industry for the synthesis of complex molecules and in the development of new drug candidates. It is also utilized in the polymer industry for the modification of polymer properties, and in the sensor industry for the creation of sensitive detection devices. Its unique chemical structure makes it valuable in these applications.
What precautions should be taken when handling (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid (CAS: 865352-21-2)?
Precautions when handling (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid include the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be conducted in a well-ventilated area or fume hood to minimize inhalation exposure. Spills should be cleaned up with care using appropriate absorbents, and the area should be thoroughly washed down. Consult the Safety Data Sheet (SDS) for specific hazard information and safety guidelines.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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