Compound Q&A
How is (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid (CAS: 865352-21-2) typically synthesized?
Answer
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid is typically synthesized through multistep reactions starting from fluorenylmethanol and hex-5-enoic acid, involving protection, acylation, and deprotection steps. Commonly used catalysts include strong bases like diisopropylethylamine, and the overall yield is usually around 70-80%. Selectivity for the desired stereoisomer is achieved through careful control of reaction conditions.
About
CAS No
865352-21-2
English Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-enoic acid
Molecular Formula
C21H21NO4
Molecular Weight
351.4020000000001 g/mol
SMILES
C=CCC[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(O)=O
InChIKey
CPJQXKHZCVDRSX-LJQANCHMSA-N
Last Updated: 2025-11-07 19:01
