4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide

Basic Information

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CAS Number

82222-74-0

Molecular Formula

C10H12ClNO2S

Molecular Weight

245.73 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

155.0 to 159.0 deg-C

SMILES

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C1CS(=O)(=O)CCN1C2=CC=C(C=C2)Cl

InChI

InChI=1S/C10H12ClNO2S/c11-9-1-3-10(4-2-9)12-5-7-15(13,14)8-6-12/h1-4H,5-8H2

InChIKey

IQIXFXLKPNFQGQ-UHFFFAOYSA-N

LogP

1.5748

Topological Polar Surface Area

37.38 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

290

Synonyms & References

English

4-(1,1-Dioxothiomorpholino)phenyl Chloride
FT-0641852
AC-13753
DTXSID50513296
T71362
82222-74-0
A916974
CS-0213149
MFCD07366283
4-(4-Chlorophenyl)-1lambda~6~,4-thiazinane-1,1-dione
C1935
AMY20749
4-(4-Chlorophenyl)thiomorpholine 1,1-Dioxide
AKOS015961421
4-(4-Chlorophenyl)thiomorpholine-1,1-dioxide
SCHEMBL12551114
4-(4-chlorophenyl)-1-thiomorpholine-1,1-dione
4-(4-chlorophenyl)-1,4-thiazinane 1,1-dioxide
trans-4-Hydroxy-D-proline?hydrochloride

MDL Number

MFCD07366283

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0)?

4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0) is a crystalline compound with a molecular weight of approximately 243.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. The compound is reactive, particularly towards nucleophiles and bases, making it suitable for various chemical transformations. It features a thiomorpholine ring with a chlorophenyl substituent, which influences its reactivity and solubility properties.

How is 4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0) typically synthesized?

4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide is typically synthesized through the condensation of 4-chlorophenyl isothiocyanate with morpholine. Commonly, this reaction is conducted in the presence of a base like triethylamine to promote the formation of the desired product. The reaction yield can be improved by using catalysts and optimizing reaction conditions such as temperature and solvent choice.

What industries use 4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0)?

4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0) is used in various industries due to its unique chemical properties. It is particularly valuable in pharmaceuticals for the synthesis of certain drugs, in polymer science for developing specialized materials, and in the production of sensors and semiconductors where its functional groups can be utilized for specific applications.

What precautions should be taken when handling 4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0)?

When handling 4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide (CAS: 82222-74-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or under a fume hood to minimize exposure to the compound. In case of a spill, use appropriate spill response materials and avoid contact with skin or eyes. Always consult the Safety Data Sheet (SDS) for detailed handling and storage information.