2-Chloro-6-fluorobenzoyl chloride

Basic Information

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CAS Number

79455-63-3

Molecular Formula

C7H3Cl2FO

Molecular Weight

193 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

106-108 ºC (15 mmHg)

Density

1.43

Flash Point

93 °C

Refractive Index

1.525

SMILES

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C1=CC(=C(C(=C1)Cl)C(=O)Cl)F

InChI

InChI=1S/C7H3Cl2FO/c8-4-2-1-3-5(10)6(4)7(9)11/h1-3H

InChIKey

GFNAJZAKJGKJCS-UHFFFAOYSA-N

LogP

2.8581000000000003

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

163

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

C2229
FT-0611855
2-chloro-6-fluorobenzoyl chloride, AldrichCPR
AKOS009159342
DTXSID20229695
GFNAJZAKJGKJCS-UHFFFAOYSA-N
NS00062254
Benzoyl chloride, 2-chloro-6-fluoro-
2-chloro-6-fluorobenzene-1-carbonyl chloride
2-chloro-6-fluoro-benzoic acid chloride
2-chloro-6-fluoro benzoyl chloride
SCHEMBL476873
W-104262
6-chloro-2-fluorobenzoyl chloride
SY049328
2-Chloro-6-fluorobenzoyl chloride
2-fluoro-6-chlorobenzoyl chloride
79455-63-3
F2190-0071
EINECS 279-162-1
2-Chloro-6-fluoro-benzoyl chloride
2-chloro-6-fluorobenzoylchloride
PS-10774
EN300-215204
CK1089
MFCD00178746
A839692
2-chloro-6-fluorobenzoyl chloride
2-Chloro-6-fluorobenzene-1-carbonyl chloride
2-Chloro-6-Fluorbenzoyl Chloride
2-Chloro-6-fluorobenzoylchloride

MDL Number

MFCD00178746

Customs Code

2916399090

FAQ

What are the physical and chemical properties of 2-Chloro-6-fluorobenzoyl chloride (CAS: 79455-63-3)?

2-Chloro-6-fluorobenzoyl chloride is a white or off-white crystalline solid with a molecular weight of 216.01 g/mol. It has a low solubility in water but is soluble in organic solvents like dichloromethane and acetonitrile. The compound is highly reactive, particularly towards nucleophiles, and can undergo substitution reactions.

How is 2-Chloro-6-fluorobenzoyl chloride (CAS: 79455-63-3) typically synthesized?

2-Chloro-6-fluorobenzoyl chloride is typically synthesized by the condensation of 2-chloro-6-fluorobenzamide with phosgene in the presence of a catalyst like N,N-dimethylformamide (DMF). The reaction yields a single product with good selectivity and moderate to high yield, depending on the conditions.

What industries use 2-Chloro-6-fluorobenzoyl chloride (CAS: 79455-63-3)?

2-Chloro-6-fluorobenzoyl chloride is used in various industries, including pharmaceuticals for the synthesis of intermediates, polymers for functional materials, and sensors for detection purposes. It is also utilized in the development of semiconductors due to its reactivity and functional groups.

What precautions should be taken when handling 2-Chloro-6-fluorobenzoyl chloride (CAS: 79455-63-3)?

When handling 2-Chloro-6-fluorobenzoyl chloride, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The substance should be handled in a well-ventilated area or a fume hood due to its reactivity. Spills should be handled according to the safety data sheet (SDS) and should be neutralized with an appropriate reagent before disposal.