(R)-3-Amino-3-(2-naphthyl)-propionic Acid

Basic Information

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CAS Number

786637-72-7

Molecular Formula

C13H13NO2

Molecular Weight

215.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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C1=CC=C2C=C(C=CC2=C1)C(CC(=O)O)N

InChI

InChI=1S/C13H13NO2/c14-12(8-13(15)16)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8,14H2,(H,15,16)/t12-/m1/s1

InChIKey

JASNXOXPNZWQRV-GFCCVEGCSA-N

LogP

2.3143

Topological Polar Surface Area

63.31999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

254

Synonyms & References

English

SCHEMBL5720938
N12450
DTXSID80375920
AM9448
H-Gly(2-Naph)-(C#CH2)OH
MFCD04113647
(R)-3-Amino-3-(naphthalen-2-yl)propanoic acid
(R)-3-Amino-3-(2-naphthyl)-propionic acid
(3R)-3-amino-3-naphthalen-2-ylpropanoic acid
(3R)-3-AMINO-3-(NAPHTHALEN-2-YL)PROPANOIC ACID
(3R)-3-azaniumyl-3-naphthalen-2-ylpropanoate
(R)-3-Amino-3-(naphthalen-2-yl)propanoicacid
D-beta-Ala-(2-naphthyl)-OH
AKOS010393646
(r)-3-amino-3-(2-naphthyl)propanoic acid
AS-66854
786637-72-7
(R)-3-Amino-3-(2-naphthyl)propionic acid
(R)-3-AMINO-3-(2-NAPHTHYL)PROPIONIC ACID,
2-Naphthalenepropanoicacid, b-amino-, (bR)-
(R)- 3-Amino-3-(2-naphthylphenyl)-propionic acid
(3R)-3-AMINO-3-(2-NAPHTHYL)PROPANOIC ACID
H-D-b-Ala-(2-naphthyl)-OH

MDL Number

MFCD04113647

FAQ

What are the physical and chemical properties of (R)-3-Amino-3-(2-naphthyl)-propionic Acid (CAS: 786637-72-7)?

(R)-3-Amino-3-(2-naphthyl)-propionic Acid is a white crystalline solid with a molecular weight of approximately 257.24 g/mol. It has a pKa of around 9.3 and is slightly soluble in water. The compound is known for its stability under normal conditions but can react with strong acids or bases. It is poorly soluble in organic solvents like ethanol and acetone but dissolves in more polar solvents like methanol and acetonitrile.

How is (R)-3-Amino-3-(2-naphthyl)-propionic Acid (CAS: 786637-72-7) typically synthesized?

(R)-3-Amino-3-(2-naphthyl)-propionic Acid can be synthesized through a multistep process involving acylation of 2-naphthol followed by aminoation. The synthesis typically involves the use of acetic anhydride for acylation, and hydrazine or an appropriate amine for the aminoation step. The reaction conditions include the use of a catalytic amount of a base like potassium carbonate to enhance the reaction yield and selectivity.

What industries use (R)-3-Amino-3-(2-naphthyl)-propionic Acid (CAS: 786637-72-7)?

(R)-3-Amino-3-(2-naphthyl)-propionic Acid finds application in the pharmaceutical industry as a precursor in the synthesis of bioactive compounds. It is also used in the polymer industry for functionalization purposes. Additionally, it can be used in the development of sensors and as a building block in the synthesis of various organic materials.

What precautions should be taken when handling (R)-3-Amino-3-(2-naphthyl)-propionic Acid (CAS: 786637-72-7)?

When handling (R)-3-Amino-3-(2-naphthyl)-propionic Acid, it is essential to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed information on proper handling and emergency procedures.