How is (R)-3-Amino-3-(2-naphthyl)-propionic Acid (CAS: 786637-72-7) typically synthesized?

(R)-3-Amino-3-(2-naphthyl)-propionic Acid can be synthesized through a multistep process involving acylation of 2-naphthol followed by aminoation. The synthesis typically involves the use of acetic anhydride for acylation, and hydrazine or an appropriate amine for the aminoation step. The reaction conditions include the use of a catalytic amount of a base like potassium carbonate to enhance the reaction yield and selectivity.