2-Amino-3-(4-biphenylyl)propanoic acid

Basic Information

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CAS Number

76985-08-5

Molecular Formula

C15H15NO2

Molecular Weight

241.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Flash Point

213℃

SMILES

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C1=CC=C(C=C1)C2=CC=C(C=C2)CC(C(=O)O)N

InChI

InChI=1S/C15H15NO2/c16-14(15(17)18)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9,14H,10,16H2,(H,17,18)

InChIKey

JCZLABDVDPYLRZ-UHFFFAOYSA-N

LogP

2.308

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

266

Synonyms & References

English

(R)-2-amino-3-(biphenyl-4-yl)propanoic acid
AB14606
3-(4-Biphenylyl)-D-alanine
H-beta-(4-Biphenylyl)-Ala-OH;H-Bip-OH
MFCD01318879
2-amino-3-(4-phenylphenyl)propanoic acid
FT-0643526
2-AMINO-3-{[1,1'-BIPHENYL]-4-YL}PROPANOIC ACID
SCHEMBL93494
DL-4-PHENYL-PHE-OH
BDA98508
76985-08-5
MFCD03425234
2-AMINO-3-(4-BIPHENYLYL)PROPANOIC ACID
AB08756
AKOS000170983
4-Phenyl-DL-Phenylalanine
H-4-PHENYL-PHE-OH
3-([1,1'-Biphenyl]-4-yl)-2-aminopropanoic acid
H-beta-(4-Biphenylyl)-D-Ala-OH;H-D-Bip-OH
A838925
FT-0641629
FT-0643628
CS-0156431
AM83473
SC-10914
2-Amino-3-([1,1'-biphenyl]-4-yl)propanoic acid (non-preferred name)
EN300-1869949
SY015772
2-AMINO-3-BIPHENYL-4-YL-PROPIONIC ACID
CS-11320

MDL Number

MFCD03425234

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5)?

2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5) is a crystalline solid with a molecular weight of approximately 307.31 g/mol. It has a high solubility in water and poor solubility in most organic solvents. The compound is moderately reactive, showing some basic properties due to its amino group. It is stable under normal conditions but should be stored away from strong acids and bases to prevent degradation.

How is 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5) typically synthesized?

2-Amino-3-(4-biphenylyl)propanoic acid can be synthesized through a multi-step process involving coupling of 4-bromobiphenyl with 2-amino-3-bromopropanoic acid, followed by reduction and acidification. Commonly, palladium catalysts like Pd(PPh3)4 are used for the coupling reaction, and sodium borohydride is employed for the reduction step. High yield and selectivity are achieved under optimized conditions.

What industries use 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5)?

2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5) finds applications in the pharmaceutical industry for the synthesis of drug intermediates, particularly those targeting chronic diseases. It is also used in the polymer industry for the development of advanced materials and in the sensor industry for the production of highly sensitive detection devices. Additionally, it has potential uses in semiconductor applications due to its ability to form stable complexes.

What precautions should be taken when handling 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5)?

When handling 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately using absorbent materials and the area should be well ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal guidelines.