2-Amino-3-(4-biphenylyl)propanoic acid(CAS: 76985-08-5)

2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5) is a crystalline solid with a molecular weight of approximately 307.31 g/mol. It has a high solubility in water and poor solubility in most organic solvents. The compound is moderately reactive, showing some basic properties due to its amino group. It is stable under normal conditions but should be stored away from strong acids and bases to prevent degradation.

2-Amino-3-(4-biphenylyl)propanoic acid can be synthesized through a multi-step process involving coupling of 4-bromobiphenyl with 2-amino-3-bromopropanoic acid, followed by reduction and acidification. Commonly, palladium catalysts like Pd(PPh3)4 are used for the coupling reaction, and sodium borohydride is employed for the reduction step. High yield and selectivity are achieved under optimized conditions.

2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5) finds applications in the pharmaceutical industry for the synthesis of drug intermediates, particularly those targeting chronic diseases. It is also used in the polymer industry for the development of advanced materials and in the sensor industry for the production of highly sensitive detection devices. Additionally, it has potential uses in semiconductor applications due to its ability to form stable complexes.

When handling 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately using absorbent materials and the area should be well ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal guidelines.