Compound Q&A

How is 2-Amino-3-(4-biphenylyl)propanoic acid (CAS: 76985-08-5) typically synthesized?

Answer

2-Amino-3-(4-biphenylyl)propanoic acid
2-Amino-3-(4-biphenylyl)propanoic acid can be synthesized through a multi-step process involving coupling of 4-bromobiphenyl with 2-amino-3-bromopropanoic acid, followed by reduction and acidification. Commonly, palladium catalysts like Pd(PPh3)4 are used for the coupling reaction, and sodium borohydride is employed for the reduction step. High yield and selectivity are achieved under optimized conditions.

About

CAS No 76985-08-5
English Name 2-Amino-3-(4-biphenylyl)propanoic acid
Molecular Formula C15H15NO2
Molecular Weight 241.29 g/mol
SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)CC(C(=O)O)N
InChIKey JCZLABDVDPYLRZ-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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