Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (1:1) | CAS No. 765935-67-9

Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (1:1)

Basic Information

CAS Number

765935-67-9

Molecular Formula

C15H19ClN2O3

Molecular Weight

310.78 g/mol

AD

Basic Physical Properties

CCOC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCNCC3.Cl

InChI

InChI=1S/C15H18N2O3.ClH/c1-2-19-15(18)14-10-11-9-12(3-4-13(11)20-14)17-7-5-16-6-8-17;/h3-4,9-10,16H,2,5-8H2,1H3;1H

InChIKey

IQUHEEPSXHVIPO-UHFFFAOYSA-N

LogP

2.4409000000000005

Topological Polar Surface Area

54.71000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

344

Synonyms & References

English

  • 765935-67-9
  • Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate HCl
  • SCHEMBL15533143
  • ethyl 5-piperazin-1-yl-1-benzofuran-2-carboxylate;hydrochloride
  • Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate HCl
  • UNII-5CCC6FM4ZF
  • Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride
  • I11659
  • Ethyl5-(piperazin-1-yl)benzofuran-2-carboxylatehydrochloride
  • 5CCC6FM4ZF
  • 5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester hydrochloride
  • ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate (Hydrochloride)
  • BCP06424
  • DTXSID00460665
  • AKOS015999471
  • MFCD09833262
  • Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (1:1)
  • 5-(1-piperazinyl)-2-Benzofurancarboxylic acid ethyl ester Monohydrochloride
  • IQUHEEPSXHVIPO-UHFFFAOYSA-N
  • AC-26993
  • A851866
  • 2-Benzofurancarboxylic acid, 5-(1-piperazinyl)-, ethyl ester, hydrochloride (1:1)
  • CS-M1843
  • CS-13073
  • 5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester Hydrochloride
  • 5-(1-Piperazinyl)-2-
  • 5-PIPERAZIN-1-YL-BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE
  • ethyl 5-piperazin-1-yl-1-benzofuran-2-carboxylate,hydrochloride
  • EBD2200674
  • AB0001011
  • AX8230884

MDL Number

MFCD09833262

Customs Code

2933599090

FAQ

What are the physical and chemical properties of Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (CAS: 765935-67-9)?

Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride is a crystalline compound with a molecular weight of approximately 387.84 g/mol. It has a m.p. of 155-157°C. The compound is soluble in water and ethanol. It is also reactive towards bases and certain functional groups. The hydrochloride salt form enhances its solubility in aqueous media.

How is Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (CAS: 765935-67-9) typically synthesized?

Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride is typically synthesized via a multi-step process involving the condensation of ethyl benzoate with 1-piperazineethane sulfonic acid, followed by the addition of hydrochloric acid to form the hydrochloride salt. The reaction is conducted under mild conditions to ensure high yield and selectivity.

What industries use Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (CAS: 765935-67-9)?

Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride is primarily used in the pharmaceutical industry for the development of novel drugs. It can also find applications in the sensors and semiconductors industry due to its chemical properties and functional groups.

What precautions should be taken when handling Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (CAS: 765935-67-9)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling this compound. It should be stored in a fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures.

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