Compound Q&A

How is Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (CAS: 765935-67-9) typically synthesized?

Answer

Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (1:1)
Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride is typically synthesized via a multi-step process involving the condensation of ethyl benzoate with 1-piperazineethane sulfonic acid, followed by the addition of hydrochloric acid to form the hydrochloride salt. The reaction is conducted under mild conditions to ensure high yield and selectivity.

About

English Name Ethyl 5-(1-piperazinyl)-1-benzofuran-2-carboxylate hydrochloride (1:1)
Molecular Formula C15H19ClN2O3
Molecular Weight 310.781 g/mol
SMILES CCOC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCNCC3.Cl
InChIKey IQUHEEPSXHVIPO-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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