1,2-Cyclohexanediamine, platinum complex, trans- | CAS No. 63121-00-6

1,2-Cyclohexanediamine, platinum complex, trans-

Basic Information

CAS Number

63121-00-6

Molecular Formula

C8H14N2O4Pt

Molecular Weight

395.27 g/mol

EINECS

602-339-2

AD

Basic Physical Properties

O=C1C(=O)O[Pt]2(NC3CCCCC3N2)O1

InChI

InChI=1S/C6H12N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-8H,1-4H2;(H,3,4)(H,5,6);/q-2;;+4/p-2

InChIKey

DWAFYCQODLXJNR-UHFFFAOYSA-L

LogP

-1.90070

Topological Polar Surface Area

76.66000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Synonyms & References

English

  • Oxaliplatin
  • (sp-4-2)-((1r,2r)-1,2-cyclohexanediamine-n,n')(ethanedioato(2-)-O,O']platinum
  • latin
  • xalatoplatinum
  • ι-OHP
  • RP-54780
  • NSC-266046
  • Elocatin
  • trans-L-Diaminocyclohexane oxalatoplatinum
  • Oxalato(trans-(-)-1,2-cyclohexanediamine)platinum(II)
  • [SP-4-2-(IR-trans)]-(1,2-cyclohexanediamine-n,n')[ethanedioato(2-)-O,O']-platinum
  • platinum(4+) cyclohexane-1,2-diyldiazanide ethanedioate (1:1:1)
  • cyclohexane-1,2-diamine
  • oxalic acid
  • platinum
  • (1R,2R)-cyclohexane-1,2-diamine
  • platinum(+2) cation
  • platinum(2+) ethanedioate (1R,2R)-cyclohexane-1,2-diamine (1:1)
  • Platinum(2+) ethanedioate - 1,2-cyclohexanediamine (1:1:1)
  • Platinum(2+) ethanedioate cyclohexane-1,2-diamine (1:1:1)
  • 1,2-CyclohexanediaMine, platinuM coMplex, trans-
  • 61825-94-3 (Sp-4-2)
  • Act 078
  • Nsc 271670
  • Oxalato(1,2-diaminocyclohexane)platinum(ii)

EC Number

602-339-2

FAQ

What are the physical and chemical properties of 1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6)?

1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6) is a crystalline solid with a molecular weight of approximately 272.24 g/mol. It is slightly soluble in water but highly soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). This complex is known for its high stability and good reactivity in various catalytic processes. It shows moderate reactivity towards various functional groups and exhibits excellent selectivity in catalytic applications.

How is 1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6) typically synthesized?

1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6) is typically synthesized by reacting cisplatin with 1,2-cyclohexanediamine in a 1:1 molar ratio. The reaction is conducted under an inert atmosphere using an appropriate solvent such as dimethyl sulfoxide (DMSO). The complex forms as a trans-arrangement of the cisplatin, which can be isolated by filtration and further purified by recrystallization.

What industries use 1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6)?

1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6) is widely used in the pharmaceutical industry for the synthesis of anticancer drugs. It is also utilized in the polymer industry for the production of advanced materials with improved catalytic properties. Additionally, this complex finds applications in the development of sensors for detecting various chemical species and in the manufacturing of semiconductors due to its unique electronic properties.

What precautions should be taken when handling 1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6)?

When handling 1,2-Cyclohexanediamine, platinum complex, trans- (CAS: 63121-00-6), it is essential to wear proper personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This complex should be handled in a well-ventilated area or inside a fume hood to minimize inhalation risks. Spills should be immediately contained and cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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