Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate | CAS No. 622369-35-1
Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate
Basic Information
CAS Number
622369-35-1
Molecular Formula
C13H12FNO4
Molecular Weight
265.24 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 7-Fluoro-1,4-dihydro-6-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
- Ethyl 7-Fluoro-6-Methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylate
- ethyl 7-fluoro-6-methoxy-4-oxo-1H-quinoline-3-carboxylate
- ethyl 7-fluoro-1,4-dihydro-6-methoxy-4-oxoquinoline-3-carboxylate
- ETHYL 7-FLUORO-4-HYDROXY-6-METHOXYQUINOLINE-3-CARBOXYLATE
- Ethyl 7-Fluoro-6-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylate
- FUJNUQDCBRIKRF-UHFFFAOYSA-N
- Ethyl7-fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate
- DTXSID60478620
- Ethyl 7-fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate
- EN300-193025
- ethyl 7-fluoro-4-hydroxy-6-methoxy-quinoline-3-carboxylate
- 851973-16-5
- SCHEMBL2031515
- DA-33666
- DB-264081
- 622369-35-1
- BP-20260
- SB69741
MDL Number
MFCD18157738
FAQ
What are the physical and chemical properties of Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1)?
Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1) is a crystalline compound with a molecular weight of approximately 333.4 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal storage conditions but should be stored away from moisture and heat to prevent hydrolysis and decomposition.
How is Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1) typically synthesized?
Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1) is typically synthesized via a multistep process involving the condensation of 7-fluoro-4-hydroxy-6-methoxyquinoline with ethyl chloroformate in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to minimize side reactions. The overall yield is around 75%, with good selectivity towards the desired product.
What industries use Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1)?
Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1) finds application in the pharmaceutical industry as an intermediate in the synthesis of various bioactive compounds. It may also be used in the polymer industry for the development of novel materials with specific functionalities. Additionally, it could be employed in the sensor industry for its unique chemical reactivity and in semiconductor manufacturing for its potential use in organic electronics.
What precautions should be taken when handling Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1)?
When handling Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately with appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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