Compound Q&A
How is Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1) typically synthesized?
Answer
Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS: 622369-35-1) is typically synthesized via a multistep process involving the condensation of 7-fluoro-4-hydroxy-6-methoxyquinoline with ethyl chloroformate in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to minimize side reactions. The overall yield is around 75%, with good selectivity towards the desired product.
About
CAS No
622369-35-1
English Name
Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate
Molecular Formula
C13H12FNO4
Molecular Weight
265.24 g/mol
SMILES
CCOC(=O)C1=CNC2=CC(=C(C=C2C1=O)OC)F
InChIKey
FUJNUQDCBRIKRF-UHFFFAOYSA-N
Last Updated: 2026-04-01 14:15
