trans-1,4-Cyclohexanedicarboxylic acid

Basic Information

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CAS Number

619-82-9

Molecular Formula

C8H12O4

Molecular Weight

172.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

>300 °C

Boiling Point

384.1℃ at 760 mmHg

Density

1.2104 (rough estimate)

Water Solubility

Soluble in hot methanol (almost transparency), ethanol, acetone. Slightly soluble in ether and water

Flash Point

200.3℃

Refractive Index

1.4795 (estimate)

SMILES

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C1[C@@H](CC[C@H](C1)C(=O)O)C(=O)O

InChI

InChI=1S/C8H12O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h5-6H,1-4H2,(H,9,10)(H,11,12)/t5-,6-

InChIKey

PXGZQGDTEZPERC-IZLXSQMJSA-N

LogP

0.962

Topological Polar Surface Area

74.6 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

169

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

trans-1,4-Cyclohexanedicarboxylic Acid
Hexahydroterephthalicacid
trans-1,4-Cyclohexanedicarboxybic acid
(1r,4r)-cyclohexane-1,4-dicarboxylic acid
1,4-Cyclohexanedicarboxylic acid,trans
e,e-trans-1,4-cyclohexanecarboxylic acid
rel-(1R,4R)-cyclohexane-1,4-dicarboxylic acid
trans-1,4-Cyclohexyldicarboxylic acid
trans-1,4-H2chdc
TRANS-CYCLOHEXAN-1,4-DICARBOXYLIC ACID
TRANS-CYCLOHEXANE-1,4-DICARBOXYLIC ACID
trans-cyclohexanedicarboxylic acid
trans-cyclohexyldicarboxylic aci
trans-Hexahydro-p-phthalic acid
trans-1,4-Cyclohexane-1,4-dicarboxylicacid
trans-4-Carboxycyclohexanecarboxylic acid
trans-Hexahydroterephthalicacid
trans-1,4-Cyclohexyldicarboxylicacid
1,4-CYCLOHEXANEDICARBOXYLIC ACID
cis-1,4-Cyclohexanedicarboxylic acid
cyclohexane-1,4-dicarboxylic acid
cis-Cyclohexane-1,4-dicarboxylic acid
Hexahydroterephthalic acid
cis-Hexahydroterephthalic acid
trans-Hexahydroterephthalic acid
1,4-Dicarboxycyclohexane
1,4-Cyclohexanedicarboxylic acid, cis-
1,4-Cyclohexanedicarboxylic acid, trans-
Terephthalic aci
trans-1,4-Cyclohexanedicarboxyli
Transtwo -1,4- cyclohexanecarboxylic acid

MDL Number

MFCD00066203

Customs Code

2917209090

FAQ

What are the physical and chemical properties of trans-1,4-Cyclohexanedicarboxylic acid (CAS: 619-82-9)?

Trans-1,4-Cyclohexanedicarboxylic acid is a colorless crystalline solid with a molecular weight of 216.23 g/mol. It has a pKa of 4.5 and is slightly soluble in water. This compound exhibits relatively low reactivity compared to other carboxylic acids, making it suitable for various chemical transformations. It has a melting point of 161-162°C and a boiling point of 234-235°C. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone.

How is trans-1,4-Cyclohexanedicarboxylic acid (CAS: 619-82-9) typically synthesized?

Trans-1,4-Cyclohexanedicarboxylic acid is typically synthesized via the oxidation of 1,4-cyclohexanedimethanol. This process involves treating the alcohol with a strong oxidizing agent such as potassium permanganate in the presence of sulfuric acid. The reaction yields a high yield of the desired diacid. Another method involves the dehydration of maleic acid to form the cis-1,4-cyclohexanedicarboxylic acid, which is then isomerized to the trans isomer under elevated temperature and pressure conditions.

What industries use trans-1,4-Cyclohexanedicarboxylic acid (CAS: 619-82-9)?

Trans-1,4-Cyclohexanedicarboxylic acid is widely used in the polymer industry, particularly in the production of polyesters and polyamides. It is also utilized in the pharmaceutical sector for the synthesis of certain drugs, as well as in the production of sensors and semiconductors. Its excellent thermal stability and chemical resistance make it a valuable component in various industrial applications.

What precautions should be taken when handling trans-1,4-Cyclohexanedicarboxylic acid (CAS: 619-82-9)?

When handling trans-1,4-Cyclohexanedicarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and a lab coat. Ensure the use of a fume hood to minimize exposure to vapor. Spills should be handled by cleaning up with appropriate neutralizing agents, followed by thorough rinsing. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions. Due to its low reactivity, it is generally safe, but proper precautions should always be taken when working with any chemical.