2,5-Dichloronicotinic acid

Basic Information

View in Editor

CAS Number

59782-85-3

Molecular Formula

C6H3Cl2NO2

Molecular Weight

192 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Solid

Melting Point

154.0 to 158.0 deg-C

Boiling Point

323.7℃ at 760 mmHg

Density

1.61

Flash Point

149.6℃

SMILES

View in Editor

C1=C(C=NC(=C1C(=O)O)Cl)Cl

InChI

InChI=1S/C6H3Cl2NO2/c7-3-1-4(6(10)11)5(8)9-2-3/h1-2H,(H,10,11)

InChIKey

SXQSMLIMBNMUNB-UHFFFAOYSA-N

LogP

2.0866000000000002

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

165

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AKOS005071148
2,5-dichloropyridine-3-carboxylic Acid
2,5-Dichloronicotinic acid, AldrichCPR
J-400181
SCHEMBL915781
59782-85-3
SY007500
AC-4668
CL0015
D4240
FT-0655740
DTXSID50371116
AM808270
Z1201621435
FT-0640637
MFCD01861979
2,5-Dichloronicotinic acid
CS-W002845
EN300-134315
2,5-DICHLORO-3-PYRIDINECARBOXYLIC ACID
3-PYRIDINECARBOXYLIC ACID, 2,5-DICHLORO-
SXQSMLIMBNMUNB-UHFFFAOYSA-N
A8388
2,5-dichloronicotinicacid
7W-0399
2,5-dichloro-3-pyridinecarboxylic acid
2,5-dichloropyridine-3-carboxylic acid
PubChem2601
PYNI16
2,5-Dichloro-nicotinic acid
KSC269G2R

MDL Number

MFCD01861979

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,5-Dichloronicotinic acid (CAS: 59782-85-3)?

2,5-Dichloronicotinic acid is a crystalline solid with a molecular weight of approximately 225.02 g/mol. It has a solubility of about 9.0 g/L in water at 25°C. The compound exhibits acidity and undergoes redox reactions. It is prone to hydrolysis under basic conditions.

How is 2,5-Dichloronicotinic acid (CAS: 59782-85-3) typically synthesized?

2,5-Dichloronicotinic acid can be synthesized by chlorinating nicotinic acid in a chlorination reaction using a Lewis acid catalyst such as aluminum chloride. The reaction yields a mixture that is then purified by recrystallization.

What industries use 2,5-Dichloronicotinic acid (CAS: 59782-85-3)?

2,5-Dichloronicotinic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the chemical industry for the production of dyes and other chemical intermediates. Additionally, it has applications in polymer synthesis and as a reagent in analytical chemistry.

What precautions should be taken when handling 2,5-Dichloronicotinic acid (CAS: 59782-85-3)?

When handling 2,5-Dichloronicotinic acid, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a dry, cool place away from direct sunlight. Spills should be cleaned up using appropriate absorbents and collected for proper disposal. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.