2,5-Dichloronicotinic acid(CAS: 59782-85-3)

2,5-Dichloronicotinic acid is a crystalline solid with a molecular weight of approximately 225.02 g/mol. It has a solubility of about 9.0 g/L in water at 25°C. The compound exhibits acidity and undergoes redox reactions. It is prone to hydrolysis under basic conditions.

2,5-Dichloronicotinic acid can be synthesized by chlorinating nicotinic acid in a chlorination reaction using a Lewis acid catalyst such as aluminum chloride. The reaction yields a mixture that is then purified by recrystallization.

2,5-Dichloronicotinic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the chemical industry for the production of dyes and other chemical intermediates. Additionally, it has applications in polymer synthesis and as a reagent in analytical chemistry.

When handling 2,5-Dichloronicotinic acid, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a dry, cool place away from direct sunlight. Spills should be cleaned up using appropriate absorbents and collected for proper disposal. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.