Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate

Basic Information

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CAS Number

372198-69-1

Molecular Formula

C10H9BrN2O2

Molecular Weight

269.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CCOC(=O)C1=CN=C2N1C=C(C=C2)Br

InChI

InChI=1S/C10H9BrN2O2/c1-2-15-10(14)8-5-12-9-4-3-7(11)6-13(8)9/h3-6H,2H2,1H3

InChIKey

VMTDOHAWLUJHAI-UHFFFAOYSA-N

LogP

2.2735000000000003

Topological Polar Surface Area

43.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

250

Synonyms & References

English

VMTDOHAWLUJHAI-UHFFFAOYSA-N
AKOS015919817
DTXSID30621803
372198-69-1
PB23824
TS-03516
SY039839
A874142
MFCD10698068
IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID, 6-BROMO-, ETHYL ESTER
SCHEMBL1649636
6-bromo-imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
CL3551
6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
FT-0738746
AM803798
Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate
Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate
6-Bromo-imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester;6-Bromo-imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester;IMidazo[1,2-a]pyridine-3-carboxylic acid, 6-broMo-, ethyl ester
CS-W022711
6-bromoImidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
ethyl 6-bromoH-imidazo[1,2-a]pyridine-3-carboxylate
IMidazo[1,2-a]pyridine-3-carboxylic acid, 6-broMo-, ethyl ester
ethyl 6-bromo-imidazo[1,2-a]pyridine-3-carboxylate
ethyl 6-bromoimidazol[1,2-a]pyridine-3-carboxylate
VMTDOHAWLUJHAI-UHF
ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate

MDL Number

MFCD10698068

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate (CAS: 372198-69-1)?

Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate is a crystalline compound with a molecular weight of approximately 285.05 g/mol. It has a low solubility in water but is soluble in common organic solvents like DMSO and DMF. This compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a dry place to avoid hydrolysis.

How is Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate (CAS: 372198-69-1) typically synthesized?

Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate is typically synthesized by the nucleophilic substitution of ethyl 6-iodimidazo[1,2-a]pyridine-3-carboxylate with bromide ion in the presence of a base such as sodium hydride. The reaction is carried out in a suitable solvent like DMF, leading to a good yield of the target compound with high selectivity.

What industries use Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate (CAS: 372198-69-1)?

Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate is used in the pharmaceutical and fine chemical industries for the synthesis of various bioactive molecules. It can also find applications in the development of sensors and materials science, particularly in the field of semiconductors and polymer science.

What precautions should be taken when handling Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate (CAS: 372198-69-1)?

When handling Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated fume hood to minimize inhalation risks. In case of a spill, immediately clean it up using appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.