2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate

Basic Information

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CAS Number

362703-48-8

Molecular Formula

C13H23NO4

Molecular Weight

257.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

323.9℃ at 760 mmHg

SMILES

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CCOC(=O)C1CCCCN1C(=O)OC(C)(C)C

InChI

InChI=1S/C13H23NO4/c1-5-17-11(15)10-8-6-7-9-14(10)12(16)18-13(2,3)4/h10H,5-9H2,1-4H3

InChIKey

KBDNAOCLKIBYPH-UHFFFAOYSA-N

LogP

2.3391

Topological Polar Surface Area

55.84 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

309

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AC-22465
MFCD03788452
AM20090576
SY023684
CS-0008353
1-tert-butyl2-ethylpiperidine-1,2-dicarboxylate
362703-48-8
Ethyl 1-Boc-piperidine-2-carboxylate
1-tert-butyl 2-ethyl piperidine-1,2-dicarboxylate
DS-11043
EN300-194062
SCHEMBL444202
J-520529
AKOS005259780
1-O-tert-butyl 2-O-ethyl piperidine-1,2-dicarboxylate
1,2-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-ethyl ester
KBDNAOCLKIBYPH-UHFFFAOYSA-N
FT-0645162
Ethyl N-Boc-piperidine-2-carboxylate
Ethyl N-BOC-pipecolinate
DTXSID20408125
1-tert-Butyl 2-ethyl piperidine-1,2-dicarboxylate
Ethyl-N-BOC-piperidine-2-carboxylate
piperidine-1,2-dicarboxylic acid-1-tert-butyl ester 2-ethyl ester
PIPERIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-ETHYL ESTER
N-Boc- Piperidine-2-carboxylate
PubChem11775
KSC222C2N
Ethyl 1-Boc-2-piperidinecarboxylate

MDL Number

MFCD03788452

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate (CAS: 362703-48-8)?

2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate is a white crystalline solid with a molecular weight of 264.39 g/mol. It has a high solubility in organic solvents like DMF and DMSO but is only slightly soluble in water. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It does not exhibit significant thermal or hydrolytic stability under normal conditions.

How is 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate (CAS: 362703-48-8) typically synthesized?

2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate is typically synthesized via esterification of 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylic acid with ethyl bromide in the presence of a base like triethylamine. The reaction is carried out in a solvent such as dichloromethane or tetrahydrofuran. The yield is generally good, with a selectivity towards the ethyl ester product.

What industries use 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate (CAS: 362703-48-8)?

2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the modification of polymeric materials to enhance their properties. Additionally, it has applications in the production of sensors and semiconductors due to its chemical functionality.

What precautions should be taken when handling 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate (CAS: 362703-48-8)?

When handling 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate, wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Store the compound in a well-ventilated area away from heat sources and incompatible materials. Use a fume hood during handling to minimize inhalation exposure. In case of a spill, immediately clean up the area using appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further guidance on disposal and cleanup procedures.