Compound Q&A

How is 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate (CAS: 362703-48-8) typically synthesized?

Answer

2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate
2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate is typically synthesized via esterification of 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylic acid with ethyl bromide in the presence of a base like triethylamine. The reaction is carried out in a solvent such as dichloromethane or tetrahydrofuran. The yield is generally good, with a selectivity towards the ethyl ester product.

About

English Name 2-Ethyl 1-(2-methyl-2-propanyl) 1,2-piperidinedicarboxylate
Molecular Formula C13H23NO4
Molecular Weight 257.33 g/mol
SMILES CCOC(=O)C1CCCCN1C(=O)OC(C)(C)C
InChIKey KBDNAOCLKIBYPH-UHFFFAOYSA-N
Last Updated: 2025-10-07 19:42

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