1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine

Basic Information

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CAS Number

340041-91-0

Molecular Formula

C11H14N2O4S

Molecular Weight

270.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

461.3 °C at 760 mmHg

Flash Point

232.8 °C

Refractive Index

1.612

SMILES

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C1CCN(C1)S(=O)(=O)CC2=CC=C(C=C2)[N+](=O)[O-]

InChI

InChI=1S/C11H14N2O4S/c14-13(15)11-5-3-10(4-6-11)9-18(16,17)12-7-1-2-8-12/h3-6H,1-2,7-9H2

InChIKey

RCEYIHLMZBWOJK-UHFFFAOYSA-N

LogP

3.06230

Complexity

384

Synonyms & References

English

SCHEMBL1425482
N-[(4-NITROPHENYL)METHYL SULFONYL]PYRROLIDINE
1-(4-Nitrophenylmethanesulfonyl)pyrrolidine
1-((4-Nitrobenzyl)sulfonyl)pyrrolidine
1-[(4-nitrobenzyl)sulfonyl]pyrrolidine
N-[(4-nitrophenyl)-methyl sulfonyl]pyryolidine
AKOS009152004
A1-01424
340041-91-0
1-[(4-nitrophenyl)methanesulfonyl]pyrrolidine
N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine
LS-08163
DTXSID80477559
RCEYIHLMZBWOJK-UHFFFAOYSA-N
4-(Pyrrolidinosulfonylmethyl) nitrobenzene
N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine;1-(4-Nitrophenylmethanesulfonyl)pyrrolidine;AP-1;N-[(4-Nitro Phenyl) Methyl sulfonyl] pyrrolidine
1-[(4-nitrophenyl)methylsulfonyl]pyrrolidine
FT-0652917
1-(((4-nitrophenyl)methyl)sulfonyl)pyrrolidine
A24952
MFCD09952023
1-[[(4-Nitrophenyl)methyl]sulfonyl]-pyrrolidine
1-[[(4-nitrophenyl)methyl]sulfonyl]Pyrrolidine
N-[(4-NITROPHENYL)-METHYL SULFONYL]PYRYOLIDINE
4-nitrobenzylsulfonyl-pyrrolidine

MDL Number

MFCD09952023

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine (CAS: 340041-91-0)?

1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine is a crystalline compound with a molecular weight of approximately 362.07 g/mol. It has limited water solubility but is more soluble in organic solvents like ethanol and acetone. The compound is known for its reactivity towards nucleophiles and its stability in acidic environments. It is sparingly soluble in water and readily soluble in organic solvents.

How is 1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) typically synthesized?

1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine is typically synthesized through the condensation of 4-nitrobenzyl bromide with pyrrolidine in the presence of a base such as potassium carbonate. The reaction is performed in an aprotic solvent like N,N-dimethylformamide (DMF) at room temperature. The yield can reach up to 85% with selectivity towards the desired product.

What industries use 1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine (CAS: 340041-91-0)?

1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also utilized in the polymer industry for the preparation of functional polymers with improved properties. Additionally, it finds applications in the development of sensors and semiconductors.

What precautions should be taken when handling 1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine (CAS: 340041-91-0)?

When handling 1-[(4-Nitrobenzyl)sulfonyl]pyrrolidine (CAS: 340041-91-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate tools and materials. In case of exposure, seek medical attention and refer to the Material Safety Data Sheet (MSDS) for further guidance.