2'-Deoxyguanosine hydrate (1:1)

Basic Information

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CAS Number

312693-72-4

Molecular Formula

C10H15N5O5

Molecular Weight

285.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

>300 °C (dec.)

Solubility

NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown

SMILES

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C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O.O

InChI

InChI=1S/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1

InChIKey

LZSCQUCOIRGCEJ-FPKZOZHISA-N

LogP

-2.4821999999999993

Topological Polar Surface Area

170.78 Å²

Hydrogen Bond Donor/Acceptor

7 / 10

Complexity

417

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

Z1741982135
J-700043
2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-onehydrate(1:x)
2'-DEOXYGUANOSINE HYDRATE, 99%
Guanine-2'-deoxyriboside
2'deoxyguanosine monohydrate
2'-Deoxyguanosine monohydrate, >=98.0% (HPLC)
PD125792
GS-3742
D72731
9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one;hydrate
2-amino-9-[(2R, 4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
2'-Deoxyguanosine hydrate
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one hydrate
Not available;2'-Deoxyguanosine hydrate
A855609
2'-Deoxyguanosinemonohydrate
LZSCQUCOIRGCEJ-FPKZOZHISA-N
AC-32158
HMS2231O12
BP-58851
2'-Deoxyguanosine monohydrate
AC-8208
AKOS015896900
SMR000875305
312693-72-4
2-Deoxyguanosine monohydrate
EN300-7385648
2'-Deoxyguanosine monohydrate, powder, BioReagent, suitable for cell culture, 99-100%

MDL Number

MFCD00150760

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2'-Deoxyguanosine hydrate (CAS: 312693-72-4)?

2'-Deoxyguanosine hydrate (CAS: 312693-72-4) is a white crystalline solid with a molecular weight of approximately 318.2 g/mol. It has a solubility of 0.14 g/100 mL in water and is moderately reactive, particularly in acidic conditions. It is stable under normal storage conditions but can degrade upon exposure to moisture or heat.

How is 2'-Deoxyguanosine hydrate (CAS: 312693-72-4) typically synthesized?

2'-Deoxyguanosine hydrate (CAS: 312693-72-4) is typically synthesized via the condensation of 2'-deoxyadenosine-5'-phosphate with guanidine in the presence of a catalyst such as sodium hydroxide. The reaction is carried out in an aqueous medium, and the product is purified by recrystallization from water, yielding a hydrate with a 1:1 ratio of 2'-deoxyguanosine to water.

What industries use 2'-Deoxyguanosine hydrate (CAS: 312693-72-4)?

2'-Deoxyguanosine hydrate (CAS: 312693-72-4) is primarily used in the pharmaceutical industry for the synthesis of nucleoside analogs used in the treatment of viral and bacterial infections. It is also utilized in the research and development of DNA and RNA-based biosensors and in the production of semiconductors as a dopant material.

What precautions should be taken when handling 2'-Deoxyguanosine hydrate (CAS: 312693-72-4)?

When handling 2'-Deoxyguanosine hydrate (CAS: 312693-72-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.