2'-Deoxyguanosine hydrate (1:1)(CAS: 312693-72-4)

2'-Deoxyguanosine hydrate (CAS: 312693-72-4) is a white crystalline solid with a molecular weight of approximately 318.2 g/mol. It has a solubility of 0.14 g/100 mL in water and is moderately reactive, particularly in acidic conditions. It is stable under normal storage conditions but can degrade upon exposure to moisture or heat.

2'-Deoxyguanosine hydrate (CAS: 312693-72-4) is typically synthesized via the condensation of 2'-deoxyadenosine-5'-phosphate with guanidine in the presence of a catalyst such as sodium hydroxide. The reaction is carried out in an aqueous medium, and the product is purified by recrystallization from water, yielding a hydrate with a 1:1 ratio of 2'-deoxyguanosine to water.

2'-Deoxyguanosine hydrate (CAS: 312693-72-4) is primarily used in the pharmaceutical industry for the synthesis of nucleoside analogs used in the treatment of viral and bacterial infections. It is also utilized in the research and development of DNA and RNA-based biosensors and in the production of semiconductors as a dopant material.

When handling 2'-Deoxyguanosine hydrate (CAS: 312693-72-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.