Ethyl L-tryptophanate hydrochloride (1:1)

Basic Information

View in Editor

CAS Number

2899-28-7

Molecular Formula

C13H17ClN2O2

Molecular Weight

268.74 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

220-225 °C (dec.)

Boiling Point

401.2°C at 760 mmHg

Flash Point

196.4 °C

Specific Rotation

10 º (c=2% in H2O)

SMILES

View in Editor

CCOC(=O)C(CC1=CNC2=CC=CC=C21)N.Cl

InChI

InChI=1S/C13H16N2O2.ClH/c1-2-17-13(16)11(14)7-9-8-15-12-6-4-3-5-10(9)12;/h3-6,8,11,15H,2,7,14H2,1H3;1H/t11-;/m0./s1

InChIKey

PESYCVVSLYSXAK-MERQFXBCSA-N

LogP

2.0226

Topological Polar Surface Area

68.11000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

270

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

L-Tryptophan ethyl ester hydrochloride
Ethyl tryptophanate hydrochloride
Ethyl L-tryptophanate HCl
L-Tryptophan ethyl ester, HCl
NSC-401579
Q96A44MQ87
TS-00882
NSC 401579
(S)-2-Amino-3-(3-indolyl)propionic Acid Ethyl Ester Hydrochloride
ethyl (2S)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride
L-Tryptophan, ethyl ester, hydrochloride (1:1)
MFCD00038993
L-Tryptophan, ethyl ester, hydrochloride
AKOS015898375
L-Trp-OEt⋅HCl
NS00083049
(S)-Tryptophan ethyl ester hydrochloride
(S)-ethyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride
Tryptophan ethyl ester hydrochloride, L-
PESYCVVSLYSXAK-MERQFXBCSA-N
H-Trp-OEt.HCl
L-tryptophan ethyl ester HCl
CHEMBL1222401
J-300271
T2981
H-TRP-OET HCL
L-Tryptophan ethyl ester hydrochloride, >=99.0% (AT)
EthylL-tryptophanatehydrochloride
H-Trp-OEt. HCl
ethyl l-tryptophanate hydrochloride
SCHEMBL133957

MDL Number

MFCD00038993

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7)?

Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7) is a crystalline compound with a molecular weight of approximately 287.8 g/mol. It is soluble in water and ethanol but less soluble in organic solvents. The compound exhibits basic properties due to the presence of the hydrochloride salt. It is relatively stable under normal conditions but can react with bases to form the free base. It has a melting point of about 210-215°C and is used in pharmaceutical formulations.

How is Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7) typically synthesized?

Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7) is typically synthesized by reacting L-tryptophan with ethyl chloroacetate in the presence of a base like sodium hydroxide. The process involves a condensation reaction followed by the addition of hydrochloric acid to form the hydrochloride salt. The reaction is carried out in an appropriate solvent, and the product is isolated by crystallization. The yield is generally around 80-90%.

What industries use Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7)?

Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the food industry as a flavoring agent and in the cosmetic industry for developing skin care products. The compound's ability to act as a precursor in the production of tryptophan analogs makes it valuable in various applications.

What precautions should be taken when handling Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7)?

When handling Ethyl L-tryptophanate hydrochloride (CAS: 2899-28-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation of dust or vapors. Spills should be cleaned up carefully, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.