(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid | CAS No. 276869-41-1

(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid

Basic Information

CAS Number

276869-41-1

Molecular Formula

C27H33NO6

Molecular Weight

467.56 g/mol

AD

Basic Physical Properties

O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCCCCC(OC(C)(C)C)=O

InChI

InChI=1S/C27H33NO6/c1-27(2,3)34-24(29)16-6-4-5-15-23(25(30)31)28-26(32)33-17-22-20-13-9-7-11-18(20)19-12-8-10-14-21(19)22/h7-14,22-23H,4-6,15-17H2,1-3H3,(H,28,32)(H,30,31)/t23-/m0/s1

InChIKey

ULPCAXORIFXUMN-QHCPKHFHSA-N

LogP

5.270500000000006

Topological Polar Surface Area

101.93 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Synonyms & References

English

  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-8-(tert-butoxy)-8-oxooctanoic acid
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-8-[(2-methylpropan-2-yl)oxy]-8-oxooctanoic acid
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)-amino)-8-(tert-butoxy)-8-oxooctanoic acid
  • (S)-2-FMOC-AMINO-OCTANEDIOIC ACID 8-TERT-BUTYL ESTER
  • (S)-Fmoc-2-Aminooctanedioic acid 8-tert-butyl ester
  • Fmoc-(S)-Asu(OtBu)-OH
  • Fmoc-Asu(OtBu)-OH
  • Fmoc-L-Asu(tBu)-OH
  • 2-(9H-fluoren-9-ylmethoxycarbonylamino)-octanedioic acid 8-tert-butyl ester
  • AK-87950
  • ANW-63201
  • FT-0686772
  • KB-210835
  • (2S)-8-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-8-oxo-octanoic acid

MDL Number

MFCD00080269

FAQ

What are the physical and chemical properties of (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid (CAS: 276869-41-1)?

This compound is an amino acid derivative with a molecular weight of approximately 483.33 g/mol. It is sparingly soluble in water but has good solubility in organic solvents such as ethanol and dichloromethane. It exhibits high reactivity due to the presence of the amino and ester functionalities. Its crystalline form allows for stable storage conditions, but it is sensitive to moisture and heat, which can lead to degradation.

How is (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid (CAS: 276869-41-1) typically synthesized?

This compound is typically synthesized through the condensation of fluorenylmethanol and α-(2-methyl-2-propanoyloxy)octanoic acid, followed by carbonylation and aminoation. Commonly used catalysts include organometallic compounds. The synthesis yields up to 85% pure product, with high selectivity towards the (2S) configuration.

What industries use (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid (CAS: 276869-41-1)?

This compound finds applications in pharmaceuticals, particularly in the development of new drugs, and in the synthesis of polymers for various industrial uses. It is also used in the production of sensors and as a key intermediate in semiconductor manufacturing due to its reactivity and specific functionality.

What precautions should be taken when handling (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid (CAS: 276869-41-1)?

When handling this compound, ensure the use of proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood due to its reactivity. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Refer to the safety data sheet (SDS) for detailed information on handling procedures and emergency response.

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