Compound Q&A

How is (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid (CAS: 276869-41-1) typically synthesized?

Answer

(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid
This compound is typically synthesized through the condensation of fluorenylmethanol and α-(2-methyl-2-propanoyloxy)octanoic acid, followed by carbonylation and aminoation. Commonly used catalysts include organometallic compounds. The synthesis yields up to 85% pure product, with high selectivity towards the (2S) configuration.

About

English Name (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-8-[(2-methyl-2-propanyl)oxy]-8-oxooctanoic acid
Molecular Formula C27H33NO6
Molecular Weight 467.56 g/mol
SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCCCCC(OC(C)(C)C)=O
InChIKey ULPCAXORIFXUMN-QHCPKHFHSA-N
Last Updated: 2025-10-28 23:23

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