5-Fluoro-2-nitroaniline

Basic Information

View in Editor

CAS Number

2369-11-1

Molecular Formula

C6H5FN2O2

Molecular Weight

156.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

96.0 to 100.0 deg-C

Boiling Point

295.5°C at 760 mmHg

Density

1.448

Water Solubility

Slightly soluble in water.

Flash Point

132.5℃

Refractive Index

1.603

SMILES

View in Editor

C1=CC(=C(C=C1F)N)[N+](=O)[O-]

InChI

InChI=1S/C6H5FN2O2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H,8H2

InChIKey

PEDMFCHWOVJDNW-UHFFFAOYSA-N

LogP

2.42050

Complexity

159

Safety Information

View Safety Information

GHS Hazard Pictograms

H373

H412

Hazard Statement

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

H412 Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

AC-3694
CS-W001110
F0789
5-Fluoro-2-Nitro Aniline
5-FLUORO-2-NITROBENZENAMINE
NSC-10292
NSC10292
GS-3014
SCHEMBL77039
EN300-57201
2-Amino-4-fluoronitrobenzene
Z600398356
8QHM7S3T84
Benzenamine, 5-fluoro-2-nitro-
5-Fluoro-2-nitroaniline
PEDMFCHWOVJDNW-UHFFFAOYSA-N
A19765
CCG-302553
AKOS005215747
W-107384
NSC 10292
AM20060247
2369-11-1
5-Fluoro-2-nitroaniline, AldrichCPR
DTXSID80178352
UNII-8QHM7S3T84
5-fluro-2-nitrophenylamine
2-Nitro-5-fluoroaniline
FT-0612080
BP-11249
EINECS 219-128-5

MDL Number

MFCD00034065

Customs Code

2921420090

FAQ

What are the physical and chemical properties of 5-Fluoro-2-nitroaniline (CAS: 2369-11-1)?

5-Fluoro-2-nitroaniline (CAS: 2369-11-1) is a crystalline solid with a molecular weight of approximately 186.04 g/mol. It is virtually insoluble in water but soluble in organic solvents such as ethanol and acetonitrile. Chemically, it is highly reactive, particularly towards reducing agents and certain nucleophiles. It is known for its limited solubility and strong reactivity in various chemical reactions.

How is 5-Fluoro-2-nitroaniline (CAS: 2369-11-1) typically synthesized?

5-Fluoro-2-nitroaniline (CAS: 2369-11-1) is typically synthesized by the reduction of 5-chloro-2-nitroaniline with a suitable reducing agent, such as sodium borohydride. This process requires careful control of the reaction conditions to achieve high selectivity and yield. The reaction is often carried out in a solvent like ethanol or water, under mild to moderate conditions.

What industries use 5-Fluoro-2-nitroaniline (CAS: 2369-11-1)?

5-Fluoro-2-nitroaniline (CAS: 2369-11-1) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry as a precursor for the production of advanced materials. Additionally, it is used in the development of sensors and as a research reagent in various scientific fields.

What precautions should be taken when handling 5-Fluoro-2-nitroaniline (CAS: 2369-11-1)?

When handling 5-Fluoro-2-nitroaniline (CAS: 2369-11-1), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The reaction should be carried out in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.