5-Fluoro-2-nitroaniline(CAS: 2369-11-1)

5-Fluoro-2-nitroaniline (CAS: 2369-11-1) is a crystalline solid with a molecular weight of approximately 186.04 g/mol. It is virtually insoluble in water but soluble in organic solvents such as ethanol and acetonitrile. Chemically, it is highly reactive, particularly towards reducing agents and certain nucleophiles. It is known for its limited solubility and strong reactivity in various chemical reactions.

5-Fluoro-2-nitroaniline (CAS: 2369-11-1) is typically synthesized by the reduction of 5-chloro-2-nitroaniline with a suitable reducing agent, such as sodium borohydride. This process requires careful control of the reaction conditions to achieve high selectivity and yield. The reaction is often carried out in a solvent like ethanol or water, under mild to moderate conditions.

5-Fluoro-2-nitroaniline (CAS: 2369-11-1) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry as a precursor for the production of advanced materials. Additionally, it is used in the development of sensors and as a research reagent in various scientific fields.

When handling 5-Fluoro-2-nitroaniline (CAS: 2369-11-1), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The reaction should be carried out in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.