(R)-2-Benzhydrylpyrrolidine hydrochloride

Basic Information

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CAS Number

23627-61-4

Molecular Formula

C17H20ClN

Molecular Weight

273.81 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CC(NC1)C(C2=CC=CC=C2)C3=CC=CC=C3.Cl

InChI

InChI=1S/C17H19N.ClH/c1-3-8-14(9-4-1)17(16-12-7-13-18-16)15-10-5-2-6-11-15;/h1-6,8-11,16-18H,7,12-13H2;1H/t16-;/m1./s1

InChIKey

KTGRJTGIWVDSKZ-PKLMIRHRSA-N

LogP

3.9923000000000024

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

220

Synonyms & References

English

(R)-2-Benzhydrylpyrrolidine hydrochloride
(2R)-2-benzhydrylpyrrolidine,hydrochloride
PYRROLIDINE, 2-(DIPHENYLMETHYL)-, HYDROCHLORIDE, (R)- (9CI)
(R)-2-(diphenylmethyl)pyrrolidine hydrochloride
(R)-(+)-2-(Diphenylmethyl)pyrrolidine HCl
PubChem23952
(2R)-(+)-2-(Diphenylmethyl)pyrrolidine hydrochloride
1616AB
OR48260
LS30036
AM62788
AX8214222
ST24026413
(2R)-2-(Diphenylmethyl)pyrrolidine--hydrogen chlorid
23627-61-4
3Y5S5QC8AN
CS-0104797
(R)-(+)-2-Benzhydrylpyrrolidine HCl
Pyrrolidine, 2-(diphenylmethyl)-, hydrochloride, (R)- (9CI)
DTXSID30705334
AKOS016011424
DB-353584
(2R)-2-(Diphenylmethyl)pyrrolidine--hydrogen chloride (1/1)
Pyrrolidine, 2-(diphenylmethyl)-, hydrochloride (1:1), (2R)-
UNII-3Y5S5QC8AN
A878183
(2R)-2-benzhydrylpyrrolidine hydrochloride
2-Diphenylmethylpyrrolidine hydrochloride, (R)-
(R)-2-Benzhydrylpyrrolidine HCl
YAA62761
AS-38668

MDL Number

MFCD14702328

FAQ

What are the physical and chemical properties of (R)-2-Benzhydrylpyrrolidine hydrochloride (CAS: 23627-61-4)?

(R)-2-Benzhydrylpyrrolidine hydrochloride is a white crystalline solid with a molecular weight of approximately 332.4 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. This compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions. It is often used in pharmaceutical and chemical synthesis due to its stability and reactivity.

How is (R)-2-Benzhydrylpyrrolidine hydrochloride (CAS: 23627-61-4) typically synthesized?

(R)-2-Benzhydrylpyrrolidine hydrochloride is typically synthesized through a multi-step process involving the formation of a pyrrolidine ring and subsequent reaction with a benzhydryl bromide derivative. The synthesis often requires the use of a Lewis acid catalyst and is known for its high yield and good selectivity, making it suitable for industrial applications.

What industries use (R)-2-Benzhydrylpyrrolidine hydrochloride (CAS: 23627-61-4)?

(R)-2-Benzhydrylpyrrolidine hydrochloride is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules and in the polymer industry for developing new materials with specific properties. It is also utilized in the production of sensors and semiconductors due to its unique chemical structure and reactivity.

What precautions should be taken when handling (R)-2-Benzhydrylpyrrolidine hydrochloride (CAS: 23627-61-4)?

When handling (R)-2-Benzhydrylpyrrolidine hydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles, to prevent skin and eye contact. Work should be conducted in a well-ventilated area with a fume hood to minimize inhalation risks. Spills should be cleaned up promptly using appropriate absorbent materials, and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.