2-Bromo-3-methyl-5-nitropyridine

Basic Information

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CAS Number

23132-21-0

Molecular Formula

C6H5BrN2O2

Molecular Weight

217.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

57.0 to 60.0 deg-C

Boiling Point

305.1℃ at 760 mmHg

Density

1.709

Flash Point

138.3°C

Refractive Index

1.599

SMILES

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CC1=CC(=CN=C1Br)[N+](=O)[O-]

InChI

InChI=1S/C6H5BrN2O2/c1-4-2-5(9(10)11)3-8-6(4)7/h2-3H,1H3

InChIKey

FZIQHPKXSLHGBZ-UHFFFAOYSA-N

LogP

2.58390

Complexity

159

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Bromo-5-nitro-3-picoline
CS-D0964
23132-21-0
FZIQHPKXSLHGBZ-UHFFFAOYSA-
W-206812
DTXSID10409464
InChI=1/C6H5BrN2O2/c1-4-2-5(9(10)11)3-8-6(4)7/h2-3H,1H3
2-bromo-3-methyl-5-nitro-pyridine
AC-15194
2-Hydroxy-5-nitro-3-picoline (2-Hydroxy-3-methyl-5-nitropyridine)
2-Bromo-3-methyl-5-nitropyridine
B2798
FZIQHPKXSLHGBZ-UHFFFAOYSA-N
A816581
MFCD03095065
AM20050976
2-bromanyl-3-methyl-5-nitro-pyridine
SY004384
EN300-1272835
SCHEMBL1028847
AKOS005257074
BCP22153
FT-0638296
Pyridine, 2-bromo-3-methyl-5-nitro-
PS-4855
6-Brom-5-methyl-3-nitropyridin
3-Picoline,2-bromo-5-nitro- (8CI)
6-Bromo-5-methyl-3-nitropyridine
ZERO/006250
PubChem10608
KSC496C3R

MDL Number

MFCD03095065

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Bromo-3-methyl-5-nitropyridine (CAS: 23132-21-0)?

2-Bromo-3-methyl-5-nitropyridine is a crystalline solid with a molecular weight of approximately 223.02 g/mol. It is slightly soluble in water but soluble in organic solvents such as ethanol and acetone. The compound is known for its high reactivity, especially towards nucleophiles and reducing agents.

How is 2-Bromo-3-methyl-5-nitropyridine (CAS: 23132-21-0) typically synthesized?

2-Bromo-3-methyl-5-nitropyridine is typically synthesized via the nitration of 3-methyl-2-pyridineboronic acid followed by bromination. This process requires careful control of reaction conditions to ensure high yield and selectivity. Commonly used reagents include nitric acid and bromine in the presence of a phase transfer catalyst.

What industries use 2-Bromo-3-methyl-5-nitropyridine (CAS: 23132-21-0)?

2-Bromo-3-methyl-5-nitropyridine is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the production of sensors and as a precursor in the development of new materials. Additionally, it is used in the semiconductor industry for specific chemical processes.

What precautions should be taken when handling 2-Bromo-3-methyl-5-nitropyridine (CAS: 23132-21-0)?

Handling 2-Bromo-3-methyl-5-nitropyridine requires strict safety measures due to its reactivity. Always wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a cool, dry place away from sources of ignition. Handle in a well-ventilated area or fume hood to avoid inhalation. In case of spill, immediately clean up using appropriate materials and consult the Safety Data Sheet (SDS) for further guidance.