1-(4-Nitrophenyl)-4-piperidinecarboxylic acid | CAS No. 223786-53-6
1-(4-Nitrophenyl)-4-piperidinecarboxylic acid
Basic Information
CAS Number
223786-53-6
Molecular Formula
C12H14N2O4
Molecular Weight
250.25 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
164-166
Safety Information
View Safety InformationHazard Statement
Hazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- 4-Piperidinecarboxylic acid, 1-(4-nitrophenyl)-
- 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid
- 1-(4-Nitrophenyl)piperidine-3-carboxylic acid
- 1-(4-nitrophenyl)piperidine-4-carboxylic acid
- AC1MCDY0
- AC1Q74M7
- CTK4E9341
- MolPort-000-894-157
- Oprea1_492432
- SBB023691
- SureCN27881
MDL Number
MFCD00664471
FAQ
What are the physical and chemical properties of 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6)?
1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6) is a white crystalline solid with a molecular weight of approximately 286.14 g/mol. It is slightly soluble in water and ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is also known for its high melting point and good stability under normal conditions.
How is 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6) typically synthesized?
1-(4-Nitrophenyl)-4-piperidinecarboxylic acid is typically synthesized via the condensation of 4-nitrophenyl chloroformate with piperidine. The reaction is carried out under anhydrous conditions, with triethylamine as a base and dichloromethane as the solvent. This method provides good selectivity and yield, making it a common approach in the chemical industry.
What industries use 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6)?
1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6) is primarily used in pharmaceuticals for the synthesis of various medicinals and also in the polymer industry for developing new materials. Additionally, it has applications in the semiconductor industry for use in sensors and electronic components.
What precautions should be taken when handling 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6)?
When handling 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6), it is crucial to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it is important to ventilate the area and use appropriate spill cleanup kits. Always consult the Safety Data Sheet (SDS) for detailed handling and storage information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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