1-(4-Nitrophenyl)-4-piperidinecarboxylic acid(CAS: 223786-53-6)

1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6) is a white crystalline solid with a molecular weight of approximately 286.14 g/mol. It is slightly soluble in water and ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is also known for its high melting point and good stability under normal conditions.

1-(4-Nitrophenyl)-4-piperidinecarboxylic acid is typically synthesized via the condensation of 4-nitrophenyl chloroformate with piperidine. The reaction is carried out under anhydrous conditions, with triethylamine as a base and dichloromethane as the solvent. This method provides good selectivity and yield, making it a common approach in the chemical industry.

1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6) is primarily used in pharmaceuticals for the synthesis of various medicinals and also in the polymer industry for developing new materials. Additionally, it has applications in the semiconductor industry for use in sensors and electronic components.

When handling 1-(4-Nitrophenyl)-4-piperidinecarboxylic acid (CAS: 223786-53-6), it is crucial to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it is important to ventilate the area and use appropriate spill cleanup kits. Always consult the Safety Data Sheet (SDS) for detailed handling and storage information.