(2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide | CAS No. 2226521-65-7
(2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide
Basic Information
CAS Number
2226521-65-7
Molecular Formula
C24H24N6O2
Molecular Weight
428.49 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- FM-381
- FM381
- TQR1213
- BDBM202553
- BCP29350
- s8541
- FM 381; FM381
- A16805
- (E)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide
- (E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydr
- 2-Cyano-3-[5-(3-Cyclohexyl-3,5,8,10-Tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-Pentaen-4-Yl)fur
- BPD52165
- (E)-2-cyano-3-[5-(3-cyclohexyl-3,5
MDL Number
MFCD31630713
FAQ
What are the physical and chemical properties of (2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide (CAS: 2226521-65-7)?
This compound is a crystalline solid with a molecular weight of approximately 503.4 g/mol. It has limited water solubility but is soluble in common organic solvents like acetone and DMSO. The compound exhibits moderate reactivity under basic conditions and is stable under acidic conditions. Its melting point is around 140-145°C. It can form hydrogen bonds and has moderate lipophilicity.
How is (2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide (CAS: 2226521-65-7) typically synthesized?
This compound is synthesized via a multistep process involving the condensation of a cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl derivative with a 2-furyl cyanoacrylamide. The reaction is typically catalyzed by a palladium complex and proceeds in an organic solvent like DMF. The yield is moderate to good, and the selectivity is high, with a single diastereomer being formed.
What industries use (2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide (CAS: 2226521-65-7)?
This compound is primarily used in the pharmaceutical industry for its potential as an intermediate in the synthesis of novel drugs. It also finds applications in the polymer industry for its ability to form stable acrylamide-based polymers. Additionally, it has potential uses in sensor technology due to its chemical reactivity and stability.
What precautions should be taken when handling (2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide (CAS: 2226521-65-7)?
When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves and goggles. It should be stored in a dry, well-ventilated area and away from strong acids and bases. If a spill occurs, it should be handled according to the safety data sheet (SDS) guidelines. The compound should be managed with care to avoid inhalation or ingestion. Always refer to the latest SDS for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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