(2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide(CAS: 2226521-65-7)

This compound is a crystalline solid with a molecular weight of approximately 503.4 g/mol. It has limited water solubility but is soluble in common organic solvents like acetone and DMSO. The compound exhibits moderate reactivity under basic conditions and is stable under acidic conditions. Its melting point is around 140-145°C. It can form hydrogen bonds and has moderate lipophilicity.

This compound is synthesized via a multistep process involving the condensation of a cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl derivative with a 2-furyl cyanoacrylamide. The reaction is typically catalyzed by a palladium complex and proceeds in an organic solvent like DMF. The yield is moderate to good, and the selectivity is high, with a single diastereomer being formed.

This compound is primarily used in the pharmaceutical industry for its potential as an intermediate in the synthesis of novel drugs. It also finds applications in the polymer industry for its ability to form stable acrylamide-based polymers. Additionally, it has potential uses in sensor technology due to its chemical reactivity and stability.

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves and goggles. It should be stored in a dry, well-ventilated area and away from strong acids and bases. If a spill occurs, it should be handled according to the safety data sheet (SDS) guidelines. The compound should be managed with care to avoid inhalation or ingestion. Always refer to the latest SDS for detailed safety information.